Temperature induced conformational transitions of elastin-like polypentapeptides studied by Raman and NMR spectroscopy

0188963 - UMCH-V 20023378 RIV NL eng J - Journal Article
Dybal, Jiří - Schmidt, Pavel - Kurková, Dana - Kříž, Jaroslav - Rodríguez-Cabello, J. C. - Alonso, M.
Temperature induced conformational transitions of elastin-like polypentapeptides studied by Raman and NMR spectroscopy.
Spectroscopy-an International Journal. Roč. 16, 3-4 (2002), s. 251-255. ISSN 0712-4813
R&D Projects: GA ČR GA203/00/1320; GA AV ČR IAA4050208
Institutional research plan: CEZ:AV0Z4050913
Keywords : quantum chemical calculations * elastin-like polypentapeptides * Raman spectra
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 0.567, year: 2002

Raman and NMR spectroscopy together with DFT quantum chemical calculations have been used to elucidate comformational changes occurring during inverse temperature transition in water solution of two elastin-like polypentapeptides, poly(G1V1G2V2P) and poly(AV1GV2P). From the temperature dependences of Raman spectra and 1H-1H NOESY spectra follows that above the transition temperature a .beta.(II)-turn conformational structure is formed on the residue located between Pro and Val1.
Permanent Link: http://hdl.handle.net/11104/0084829