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Monte Carlo simulation of radiolytic attack to 5 -d[TSUB.4GSUB.4]SUB.4 sequence in a unimolecular quadruplex
- 1.0184976 - UJF-V 20000145 RIV GB eng J - Journal Article
Běgusová, Marie - Tartier, L. - Syt, D. - Spotheim-Maurizot, M. - Michalik, Věslav - Charlier, M.
Monte Carlo simulation of radiolytic attack to 5 -d[TSUB.4GSUB.4]SUB.4 sequence in a unimolecular quadruplex.
[MC simulace účinku radikálů na 5-d [T4G4] 4 sekvence v unimolekulárním kvadruplexu.]
International Journal of Radiation Biology. Roč. 75, č. 7 (1999), s. 913-917. ISSN 0955-3002. E-ISSN 1362-3095
R&D Projects: GA AV ČR IAB1048901
Institutional research plan: CEZ:AV0Z1048901
Keywords : OH radical attack * DNA unimolecular quadruplex * Theoretical modeling
Subject RIV: BO - Biophysics
Impact factor: 2.521, year: 1999
Theoretical model has been applied to predict OH radical damage to DNA unimolecular quadruplex. Good agreement between the calculated and experimental probabilities of FSB and ARB has been found.
Teoretický model byl použit pro predikci poškození unimolekulárního kvadruplexu DNA hydroxylovými radikály. Byla zjištěna dobrá shoda mezi teoretickými a experimentálními pravděpodobnostmi FSB a ARB.
Permanent Link: http://hdl.handle.net/11104/0081401
Number of the records: 1