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Voltammetric Determination of Cytostatic Using Silver Solid Amalgam Electrode
- 1.0181651 - UFCH-W 20030077 RIV CZ eng C - Conference Paper (international conference)
Barek, J. - Fischer, J. - Konečná, B. - Kratzer, J. - Hrušková, M. - Navrátil, Tomáš - Novotný, Ladislav - Josypčuk, Bohdan - Zima, J.
Voltammetric Determination of Cytostatic Using Silver Solid Amalgam Electrode.
Moderní elektrochemické metody. Praha: Česká společnost chemická, 2003 - (Barek, J.; Navrátil, T.; Novotný, L.), s. 16-19. ISBN 80-86238-29-6.
[Moderní elektrochemické metody /23./. Jetřichovice (CZ), 20.05.2003-22.05.2003]
Grant - others:GIT(AR) 101/02/U111/CZ
Institutional research plan: CEZ:AV0Z4040901
Keywords : 6-mercaptupurine * mitoxantrone * doxorubicin
Subject RIV: CG - Electrochemistry
Modern polarographic and voltammetric methods at mercury meniscus-modified silver solid amalgam electrode (m-AgSAE) were proved to be suitable for the determination of a number of polarographically active cytostatic drugs. The voltammetric determination of 6-mercaptupurine (6-MP), 6-thioguanine (6-TG), Mitoxantrone (MX, CAS No.: 65271-80-9, CAS. Name: 1,4-Dihydroxy-5,8-bis[{2-[(2-hydroxyethyl)amino]ethyl}amino]-9,10-anthracenedione), and Doxorubicin (DR, CAS No.: 23214-92-8, CAS Name: (8S-cis)-10-[(3-Amino-2,3,6-trideoxy--L-lyxohexapyranosyl)oxy] - 7, 8, 9, 10 - tetrahydro-6, 8, 11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphtacenedione) were studied.
Permanent Link: http://hdl.handle.net/11104/0078186
Number of the records: 1