0173808 - UEM-P 20033134 RIV US eng J - Journal Article
Frisch, CH. - Theis, M. - Silva, M. A. - Dere, E. - Sohl, G. - Teubner, B. - Náměstková, Kateřina - Willecke, K. - Huston, J. P.
Mice with astrocyte-directed inactivation of connexin43 exhibit increased exploratory behaviour, impaired motor capacities, and changes in brain acetylcholine levels.
European Journal of Neuroscience. Roč. 18, - (2003), s. 2313-2318. ISSN 0953-816X. E-ISSN 1460-9568
Institutional research plan: CEZ:AV0Z5039906
Keywords : neuron-glia interactions
Subject RIV: FH - Neurology
Impact factor: 3.872, year: 2003

We investigated the effects of the astrocyte-directed inactivation of Cx43 (gap junctions forming connexin protein) on mouse behaviour and brain neurochemistry. Transgenic animals showed increased exploration in the open field and steeper learning course in water maze, they showed increased acetylcholine content in the frontal cortex.
Permanent Link: http://hdl.handle.net/11104/0070834