Diffusion Parameters of the Extracellular Space in Human Gliomas

0173727 - UEM-P 20033048 RIV US eng J - Journal Article
Vargová, L. - Homola, A. - Zámečník, J. - Tichý, M. - Beneš, V. - Syková, Eva
Diffusion Parameters of the Extracellular Space in Human Gliomas.
Glia. Roč. 42, č. 1 (2003), s. 77-88. ISSN 0894-1491. E-ISSN 1098-1136
R&D Projects: GA ČR GA309/00/1430
Institutional research plan: CEZ:AV0Z5039906; CEZ:MSM 111300004; CEZ:MZd 00000064203
Keywords : apparent diffusion coefficient * brain tumors
Subject RIV: FH - Neurology
Impact factor: 4.677, year: 2003

The diffusion parameters in temporal cortical tissue resected during surgical treatment of temporal lobe epilepsy (control) were compared with those in brain tumors and tumor slices were histopathologically classified. Tumor malignancy grade strongly corresponded to an increase in extracellular space volume, which was accompanied by a change in extracellular space structure manifested by an increase in diffusion barriers for small molecules.
Permanent Link: http://hdl.handle.net/11104/0070753