0173590 - UEM-P 20023035 RIV ES eng J - Journal Article
Ešner, M. - Pacherník, J. - Hampl, Aleš - Dvořák, Petr
Targeted disruption of fibroblast growth factor receptor 1 blocks maturation of visceral endoderm and cavitation in embryoid bodies.
International Journal of Developmental Biology. Roč. 46, - (2002), s. 817-825. ISSN 0214-6282. E-ISSN 1696-3547
R&D Projects: GA MŠMT ME 198
Institutional research plan: CEZ:AV0Z5039906; CEZ:MSM 432100001
Keywords : embryoid body * differentiation
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.465, year: 2002

Study analyzes the effects of the absence of basic fibroblast growth factor receptor (FGFR-1) in mouse embryonic stem cells using embryoid bodies as a model. The results show that FGFR-1 deficiency results in defect in visceral endoderm maturation that most likely underlies the previously found abnormalities in mesoderm formation.
Permanent Link: http://hdl.handle.net/11104/0070620