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The oncogenic RAS2 val19 mutation locks respiration, independently of PKA, in a mode prone to generate ROS

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    0154959 - MBU-M 20030302 RIV GB eng J - Journal Article
    Hlavatá, Lydie - Aguilaniu, H. - Pichová, Alena - Nystrom, T.
    The oncogenic RAS2 val19 mutation locks respiration, independently of PKA, in a mode prone to generate ROS.
    EMBO Journal. Roč. 22, č. 13 (2003), s. 3337-3345. ISSN 0261-4189. E-ISSN 1460-2075
    R&D Projects: GA ČR GA301/03/0289
    Institutional research plan: CEZ:AV0Z5020903
    Keywords : pka/ras2/ * ucp1 * respiratory state
    Subject RIV: EE - Microbiology, Virology
    Impact factor: 10.456, year: 2003

    The RAS2val19 allele, which renders the cAMP-PKA pathway constitutively active and decreases the replicative life-span of yeast cells.
    Permanent Link: http://hdl.handle.net/11104/0052440

     
     

Number of the records: 1  

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