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Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data
- 1.0154801 - MBU-M 20030170 RIV NL eng J - Journal Article
Říhová, Blanka - Strohalm, Jiří - Prausová, J. - Kubáčková, K. - Jelínková, Markéta - Rozprimová, L. - Šírová, Milada - Plocová, Daniela - Etrych, Tomáš - Šubr, Vladimír - Mrkvan, Tomáš - Kovář, Marek - Ulbrich, Karel
Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data.
Journal of Controlled Release. Roč. 91, - (2003), s. 1-16. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA ČR GA305/02/1425; GA AV ČR IBS5020101; GA AV ČR IAA4050201; GA ČR GA310/99/P020
Institutional research plan: CEZ:AV0Z4050913; CEZ:AV0Z5020903
Keywords : hpma * human immunoglobulin * targeted therapy
Subject RIV: EE - Microbiology, Virology
Impact factor: 3.298, year: 2003
An N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier containing doxorubicin and human immunoglobulin as an actively passively targeting moiety was used in four patients with generalized breast cancer resistant to standard cytotoxic chemotherapy.
Permanent Link: http://hdl.handle.net/11104/0052285
Number of the records: 1