Th1 and Th2 cytokine profile in patiens with early onset periodontitis and their healthy siblings

0153939 - MBU-M 20010003 RIV GB eng J - Journal Article
Bártová, J. - Krátka-Opatrná, Z. - Procházková, J. - Krejsa, O. - Dušková, J. - Mrklas, L. - Tlaskalová, Helena - Cukrowska, Božena
Th1 and Th2 cytokine profile in patiens with early onset periodontitis and their healthy siblings.
Mediators of Inflammation. Roč. 9, - (2000), s. 115-120. ISSN 0962-9351. E-ISSN 1466-1861
R&D Projects: GA MZd NK5006
Institutional research plan: CEZ:AV0Z5020903
Keywords : early onset periodontitis * immunoglobulin
Subject RIV: EC - Immunology
Impact factor: 0.990, year: 2000

We tested the hypothesis about the role of Th1 and Th2 cytokines in the pathogenesis of early onset periodontitis (EOP). Th1 and Th2 cytokine production was measured after in vitro stimulation. Peripheral blood mononuclear cells actinomycetemcomitans or Escherichia coli. After in vitro stimulation of PBMC, a significantly higher production of IFN-gamma were found.
Permanent Link: http://hdl.handle.net/11104/0051431