Adhesion, differentiation and immune activation of human osteogenic cells in cultures on carbon-fibre reinforced carbon composites

0142570 - FGU-C 20030177 RIV PL eng J - Journal Article
Bačáková, Lucie - Starý, V. - Glogar, Petr - Lisá, Věra
Adhesion, differentiation and immune activation of human osteogenic cells in cultures on carbon-fibre reinforced carbon composites.
Engineering of Biomaterials. Roč. 6, - (2003), s. 8-9. ISSN 1429-7248.
[Konferencja Naukowa "Biomaterialy w medycynie i weterynarii" /13./. Rytro, 09.10.2003-12.10.2003]
R&D Projects: GA MŠMT OC 527.130
Institutional research plan: CEZ:AV0Z3046908; CEZ:AV0Z5011922
Keywords : carbon-carbon composites * surface properties * bone tissue engineering
Subject RIV: JI - Composite Materials

Carbon fibre-reinforced carbon composites (CFRC), promising materials for hard tissue surgery, were treated by grinding with metallographic paper, coating with pyrolytic graphite and polishing with diamond paste. This treatment improved adhesion, growth and osteocalcin production in osteogenic MG 63 cells in vitro. On thee other hand, the concentration of ICAM-1, which binds immunocompetent cells, was not increased, and the release of carbon particles from the material was significantly diminished.
Permanent Link: http://hdl.handle.net/11104/0040271