Actions of lyotropic anions on the mechanical properties of fast and slow twitch rat muscles at different temperatures

0142458 - FGU-C 20030062 RIV CZ eng J - Journal Article
Wondmikun, Y. - Soukup, Tomáš - Asmussen, G.
Actions of lyotropic anions on the mechanical properties of fast and slow twitch rat muscles at different temperatures.
Physiological Research. Roč. 52, č. 1 (2003), s. 123-129. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR GA304/00/1653
Grant - others:Deutsche Forschungsgemeinschaft(DE) -; Schwerpunkt Muskelforschung(DE) As 74/1-2
Institutional research plan: CEZ:AV0Z5011922
Keywords : slow and fast muscles * contractile properties * lyotropic anions
Subject RIV: FH - Neurology
Impact factor: 0.939, year: 2003

The effects of lyotropic anions on contractile properties of fast-twitch extensor digitorum longus and slow-twitch soleus muscles were investigated in vitro at 20 oC and 25 oC. Muscles bathed in anionic Tyrode solution were stimulated directly and isometric single twitches and fused tetanic contractions were recorded. In a Tyrode solution a decrease of the bathing temperature led to a cold potentiation of the twitch tension in EDL muscles, however, to a cold depression in SOL muscles, in both muscles combined with a prolongation of contraction and half relaxation times. The extent and order of potentiating effect of lyotropic anions were quite similar and increased. Since the lyotropic anions did not influence tetanic tensions, the twitch-tetanus ratio was increased. All effects of the anions were rapidly and completely reversed in both muscles when the test solution was replaced by the normal one. The temperature decrease caused no significant alteration in the potentiation capacity of the actions or in the kinetics of their action and reversibility.
Permanent Link: http://hdl.handle.net/11104/0040161