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Effect of increased pressure loading on heart growth in neonatal rats
- 1.0142450 - FGU-C 20030054 RIV GB eng J - Journal Article
Sedmera, D. - Thompson, R. P. - Kolář, František
Effect of increased pressure loading on heart growth in neonatal rats.
Journal of Molecular and Cellular Cardiology. Roč. 35, č. 3 (2003), s. 301-309. ISSN 0022-2828. E-ISSN 1095-8584
R&D Projects: GA ČR GA305/01/0279; GA MŠMT LN00A069
Grant - others:NIH(US) HL50582
Institutional research plan: CEZ:AV0Z5011922
Keywords : aortic constriction * cardiomyocyte proliferation * hypertrophy
Subject RIV: ED - Physiology
Impact factor: 4.954, year: 2003
We studied the growth response of the rat left ventricle to pressure overload induced by aortic constriction at postnatal day 2. The results suggest that adaptation of the neonatal myocardium to increased load is rapid, and is based on transitory hyperplasia followed by hypertrophy of myocytes.
Permanent Link: http://hdl.handle.net/11104/0040153
Number of the records: 1