Intrafusal fiber type composition of muscle spindles in the first human lumbrical muscle

0142416 - FGU-C 20030008 RIV US eng J - Journal Article
Soukup, Tomáš - Pedrosa-Domellöf, F. - Thornell, L. E.
Intrafusal fiber type composition of muscle spindles in the first human lumbrical muscle.
Acta Neuropathologica. Roč. 105, č. 1 (2003), s. 18-24. ISSN 0001-6322. E-ISSN 1432-0533
R&D Projects: GA ČR GA304/00/1653
Grant - others:Swedish Medical Research Council(SE) 12X-3934
Institutional research plan: CEZ:AV0Z5011922
Keywords : Human lumbrical muscle * muscle spindle * myofibrillar ATPase activity
Subject RIV: FH - Neurology
Impact factor: 2.556, year: 2003

Muscle spindles exhibited a marked variability with respect to the number, position, length and detailed histochemical features of nuclear bag1, nuclear bag2 and nuclear chain fibers. Regarding mATPase activity, the nuclear bag2 fibers displayed lower alkali-stable mATPase activity along their length and many nuclear bag1 fibers tended to have lower acid-stable activity in the outer B region, whereas nuclear chain fibers exhibited medium acid-stable mATPase activity at pH 4.6. Muscle spindles in the first human lumbrical muscle contained more intrafusal fibers and especially relatively more nuclear bag fibers compared to other human skeletal muscles. Since each spindle apparently represents a unique morphological and physiological entity, the observed variability in the number and characteristics of intrafusal fibers in the first human lumbrical muscle likely reflects a wide range o finely tuned muscle spindle responses.
Permanent Link: http://hdl.handle.net/11104/0040120