Adhesion, growth and stress adaptation of vascular smooth muscle cells in cultures on collagen I degraded by matrix metalloproteinases-13

0142395 - FGU-C 20020118 RIV CZ eng K - Conference Paper (Czech conference)
Bačáková, Lucie - Herget, J. - Novotná, J. - Eckhardt, Adam - Lisá, Věra
Adhesion, growth and stress adaptation of vascular smooth muscle cells in cultures on collagen I degraded by matrix metalloproteinases-13.
Atherosklerosa. Hyperhomocysteinemie 2002: diagnostika, léčba, prevence. Praha: Společnost patologické a klinické fyziologie ČLS JEP Sekce pro atherosklerosu, IV. interní klinika 1. LF UK, 2002, s. 1-5. ISBN 80-238-9322-X.
[Atherosklerosa. Hyperhomocysteinemie 2002: diagnostika, léčba, prevence. Praha (CZ), 11.09.2002-13.09.2002]
R&D Projects: GA ČR GA305/97/S070; GA ČR GA304/02/1348; GA MŠMT LN00A069
Institutional research plan: CEZ:AV0Z5011922
Keywords : integrins - vinculin * talin
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

Degradation of collagen I by matrix metalloproteinase-13 resulted in a lower adhesion, higher proliferation, higher concentration of heath shock protein 60, higher cell death and loss of differentiation markers in rat aortic smooth muscle cells in cultures on this substrate.
Permanent Link: http://hdl.handle.net/11104/0040099