0142302 - FGU-C 20020024 RIV NL eng J - Journal Article
Lyfenko, Alla - Vlachová, Viktorie - Vyklický st., Ladislav - Dittert, Ivan - Kress, M. - Reeh, P. W.
The effects of excessive heat on heat-activated membrane currents in cultured dorsal root ganglia neurons from neonatal rat.
Pain. Roč. 95, č. 3 (2002), s. 207-214. ISSN 0304-3959. E-ISSN 1872-6623
R&D Projects: GA ČR GA305/00/1639; GA MŠMT LN00B122
Institutional research plan: CEZ:AV0Z5011922
Keywords : nociception * noxious heat * capsacin
Subject RIV: ED - Physiology
Impact factor: 4.829, year: 2002

It is suggested that exposure of nociceptive neurons to excessive noxious heat results in an irreversible decrease of the energy barrier between the resting and activated state of the protein structures responsible for generation of Iheat. This may explain the sensitization of nociceptors after heat injury.
Permanent Link: http://hdl.handle.net/11104/0040008