Bromide kinetics and distribution in the rat. I. biokinetics of 82Br-bromide

0142055 - FGU-C 20000093 RIV US eng J - Journal Article
Pavelka, Stanislav - Babický, Arnošt - Vobecký, Miloslav - Lener, J. - Švandová, E.
Bromide kinetics and distribution in the rat. I. biokinetics of 82Br-bromide.
Biological Trace Element Research. Roč. 76, l (2000), s. 57-66. ISSN 0163-4984. E-ISSN 1559-0720
R&D Projects: GA AV ČR IAA7011813
Subject RIV: ED - Physiology
Impact factor: 0.786, year: 2000

Biological half-lives of bromine in 15 different organs and tissuesof the rat, in addition to the whole-life, were determined bymeasuring the radioactive concentration of 82Br-bromide in samplesof tissues collected at the time intervals of 12-396 h from animalsthat continuously (up to 17 d) received 82Br-labeled bromide in theirdrinking water. In most of the studied tissues, the biological half-lives of bromine were shorter than in the whole body, in which itequaled 197.8 + - 22.2 h. Significant correlation between the valuesof the steady-state concentration of bromide and of the biologicalhalf-life was found for most tissues.
Permanent Link: http://hdl.handle.net/11104/0039764