Chemiluminescence at the Turn of the Millennium. An indispensible Tool in modern Chemistry, Biochemistry and Medicine

0126503 - BFU-R 20013063 RIV DE eng M - Monography Chapter
Kubala, Lukáš - Číž, Milan - Lojek, Antonín - Studeník, P. - Černý, J. - Soška, V.
Oxidative Stress in Patients with Regular Hemodialysis Measured by Chemiluminescence.
Chemiluminescence at the Turn of the Millennium. An indispensible Tool in modern Chemistry, Biochemistry and Medicine. Dresden: SCHWEDAWERBEDRUCK GmbH, Druckerei and Verlag, 2001 - (Albrecht, S.; Zimmermann, T.; Brandl, H.), s. 264-269. ISBN 3-9807853-0-0
R&D Projects: GA AV ČR IBS5004009; GA MZd NA4796
Institutional research plan: CEZ:AV0Z5004920
Keywords : oxidative stress * chemiluminescence
Subject RIV: BO - Biophysics

The aim of the study was to examine the phagocyte-derived production of reactive oxygen species, the expression of surface receptors and the total peroxyl radical-trapping antioxidant potential of plasma in patients with regular hemodialysis. The decline of reactive oxygen species generation and the increased expression of CD11b both on neutrophils and monocytes was found after hemodialysis. The antioxidant potential of plasma before hemodialysis treatment was higher when compared with healthy controls. However, it decreased significantly even below this of healthy controls after the treatment. In conclusion, chemiluminiscence can be a very important tool for the assessment of various parameters of oxidative stress. Decreased peroxyl radical-trapping antioxidant potential of plasma indicates insufficient antioxidant defence in patients with chronic renal failure
Permanent Link: http://hdl.handle.net/11104/0024731