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NMR (13)C-relaxation study of base and sugar dynamics in GCAA RNA hairpin tetraloop

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    0089118 - BC 2008 RIV US eng J - Journal Article
    Trantírek, Lukáš - Caha, E. - Kadeřávek, P. - Fiala, R.
    NMR (13)C-relaxation study of base and sugar dynamics in GCAA RNA hairpin tetraloop.
    [Studium dynamiky bazí a cukrů ve smyčce GCAA pomocí 13C-relaxace NMR.]
    Journal of Biomolecular Structure & Dynamics. Roč. 25, č. 3 (2007), s. 243-252. ISSN 0739-1102
    R&D Projects: GA ČR GA203/05/0388; GA MŠMT(CZ) LC06030
    Grant - others:GA ČR(CZ) GA203/99/0311; EU FSG-V-RNA, 6th Framework Program EU
    Institutional research plan: CEZ:AV0Z60220518
    Source of funding: R - Framework programmes of European Commission
    Keywords : RNA * GNRA * NMR * GCAA * relaxation * dynamics * hairpin * tetraloop
    Subject RIV: CE - Biochemistry
    Impact factor: 1.413, year: 2007

    Intramolecular dynamics of a 14-mer RNA hairpin including GCAA tetraloop was investigated by (13)C NMR relaxation. R(1) and R(1rho) relaxation rates were measured for all protonated base carbons as well as for C1' carbons of ribose sugars at several magnetic field strengths.

    Intramolekulární dynamika RNA 14-ti meru zahrnujícího GCAA smyčku by charakterizována pomocí 13C relaxace NMR. Relaxacni rychlosti, R1 a R1 ρ pro všechny protonované uhlíky bazí a C1’ uhlíky cukrerných jednotek byly naměřeny při několika intenzitách magnetického pole.
    Permanent Link: http://hdl.handle.net/11104/0150447

     
     
Number of the records: 1  

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