Hirtusneanoside, an Unsymmetrical Dimeric Tetrahydroxanthone from the Lichen Usnea hirta

0088908 - MBÚ 2008 RIV SIGLE US eng J - Journal Article
Řezanka, Tomáš - Sigler, Karel
Hirtusneanoside, an Unsymmetrical Dimeric Tetrahydroxanthone from the Lichen Usnea hirta.
[Hirtusneanosid, nesymetrický dimerní tetrahydroxanthon z lišejníku Usnea hirta.]
Journal of Natural Products. Roč. 70, - (2007), s. 1487-1491. ISSN 0163-3864. E-ISSN 1520-6025
Institutional research plan: CEZ:AV0Z50200510
Keywords : usnea hirta * hirtusneanoside * gram-positive bacteria
Subject RIV: EE - Microbiology, Virology
Impact factor: 2.551, year: 2007

A novel O-deoxyglycoside of a dimeric tetrahydroxanthone, named hirtusneanoside, was isolated from the lichen Usnea hirta. Its structure, including the absolute configurations of the hydroxyl and methyl groups, and biphenyl moiety, was determined by means of extensive spectroscopic data (UV, IR, MS, CD, 1D and 2D NMR) and chemical degradation. Hirtusneanoside has a unique structure containing a tetrahydroxanthone dimer of O-glycoside with a L-rhamnopyranosyl unit, and showed growth inhibitory activities against Gram-positive bacteria

Z lišejníku Usnea hirta byl izolován hirtusneanoosid, O-deoxyglukosid dimerního tetrahydroxanthonu. Jeho struktura včetně absolutní konfigurace byla stanovena spektroskopicky a chemickou degradací. Hirtusneanosid je aktivní proti Gram-pozitivním bakteriím
Permanent Link: http://hdl.handle.net/11104/0150286