Biomarkers of exposure to carcinogenic PAHs and their relationship with environmental factors

0087290 - ÚEM 2008 RIV NL eng J - Journal Article
Taioli, E. - Šrám, Radim - Binková, Blanka - Kalina, I. - Popov, T. A. - Garte, S. - Farmer, P. B.
Biomarkers of exposure to carcinogenic PAHs and their relationship with environmental factors.
[Biomarkery expozice karcinogenním PAU a jejich vztah k environmentálních faktorům.]
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. Roč. 620, - (2007), s. 16-21. ISSN 0027-5107
Grant - others:EU(GB) 2000-00091
Institutional research plan: CEZ:AV0Z50390512
Source of funding: R - Framework programmes of European Commission
Keywords : DNA adducts * air pollution * carcinogenic PAHs
Subject RIV: DN - Health Impact of the Environment Quality
Impact factor: 4.159, year: 2007

The relationships between the levels of DNA adducts (as biomarkers of exposure), the exposure to air pollution (carcinogenic PAHs) and smoking status are studied in the population from Prague, Kosice and Sofia. The results showed that B[a]P DNA adducts were more strongly associated with smoking status than with the environmental exposure to carcinogenic PAHs.

U skupin osob z Prahy, Košic a Sofie byl studován vztah mezi hladinou DNA aduktů (jako biomarkeru expozice), expozicí znečištěnému ovzduší (karcinogenním PAU) a kouřením. Výsledky ukázaly, že spojitost mezi B[a]P-DNA adukty a kouřením je mnohem silnější než vztah těchto aduktů k environmentální expozici karcinogenním PAU.
Permanent Link: http://hdl.handle.net/11104/0149185