Number of the records: 1  

The study of DNA damage-dependent cell-cycle arrest in Chlamydomonas reinhardtii

  1. 1.
    0081611 - MBÚ 2007 RIV SIGLE FR eng C - Conference Paper (international conference)
    Ševcovicová, A. - Gálová, E. - Hamzová, A. - Sviežená, B. - Hendrychová, Jana - Čížková, Mária - Vítová, Milada - Bišová, Kateřina - Zachleder, Vilém - Vlček, D.
    The study of DNA damage-dependent cell-cycle arrest in Chlamydomonas reinhardtii.
    [Studium zablokování buněčného cyklu závislé na poškození DNA u Chlamydomonas reinhardtii.]
    FESPB Congress Federation of European Societies of Plant Biology. Lyon: Verlag, 2006, s. 15-15.
    [FESPB Congress Federation of European Societies of Plant Biology. Lyon (FR), 17.07.2006-21.07.2006]
    Institutional research plan: CEZ:AV0Z50200510
    Keywords : chlamydomonas reinhardtii * dna
    Subject RIV: EE - Microbiology, Virology

    In this study, the effect of DNA damage on the progression of C. reinhardtii cell cycle has been studied. UV-irradiated wild-type cells delay cell division thereby providing time for DNA repair. Mutant strains were isolated that do not delay cell division after UV irradiation and produce inviable microcolonies. We carried out phenotypic, molecular and genetic analyses of the mutant strains. The course of growth and reproductive processes during cell cycle was also analyzed. Moreover, the presence of cyclin-dependent kinases (CDKs) and changes in kinase activity after UV irradiation were compared to those in normal conditions

    Studovali jsme vliv poškození DNA na průběh buněčného cyklu za použití izolovaného mutantního kmene Chlamydomonas reinhardtii uvs11. Byla sledována kinázová aktivita, hladina proteinů, RNA a DNA za normálních podmínek a po ozáření UV zářením. Reprodukční procesy byly monitorovány kontrolou jaderného dělení, dělení protoplastů a tvorby dceřiných buněk
    Permanent Link: http://hdl.handle.net/11104/0145423

     
     
Number of the records: 1  

  This site uses cookies to make them easier to browse. Learn more about how we use cookies.