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Study of feasibility of the treatment with procainamide hydrochloride and cisplatin in pregnant mice
- 1.0050866 - ÚEM 2007 RIV IE eng J - Journal Article
Ognio, E. - Chiavarina, B. - Peterka, Miroslav - Mariggió, M.A. - Viale, M.
Study of feasibility of the treatment with procainamide hydrochloride and cisplatin in pregnant mice.
[Studie možnosti léčby prokainamid hydrochloridem a cisplatinou u březích myší.]
Chemico-Biological Interactions. Roč. 164, č. 3 (2006), s. 232-240. ISSN 0009-2797. E-ISSN 1872-7786
R&D Projects: GA MŠMT OC B23.001
Institutional research plan: CEZ:AV0Z50390512
Keywords : Cisplatin * Embryotoxicity * Chemioprotection
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.800, year: 2006
A relevant result of this research is the suggestion that procainamide hydrochloride might be administered in case of pregnancy to protect against the maternal toxic effects of cisplatin without an increased embryotoxic/teratogenic risk for the offspring.
Výsledky tohoto výzkumu naznačují, že prokainamid hydrochlorid by mohl být podáván v těhotenství na ochranu matky proti toxickému vlivu cisplatiny, aniž by tím se tím zvýšilo embryotoxické či teratogenní riziko pro dítě.
Permanent Link: http://hdl.handle.net/11104/0140903
Number of the records: 1