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An invertebrate TNF functional analogue as a tool to reveal ancient mechanism of vertebrate macrophage activation

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    0049909 - MBÚ 2007 RIV SIGLE US eng C - Conference Paper (international conference)
    Bilej, Martin - Josková, Radka - Van den Bergh, R. - Kohlerová, Petra - Šilerová, Marcela - Ameloot, P. - De Baetselier, P. - Beschin, A.
    An invertebrate TNF functional analogue as a tool to reveal ancient mechanism of vertebrate macrophage activation.
    [Funkční analog TNF u bezobratlých jako nástroj pro studium původních mechanismů aktivace makrofágů obratlovců.]
    10th International Congress of the International Society of Developmental and Comparative Immunology /10./. Charleston: Blackwell Publishing, 2006, s. 73-73.
    [International Congress of the International Society of Developmental and Comparative Immunology /10./. Charleston (US), 01.07.2006-06.07.2006]
    R&D Projects: GA ČR GA310/04/0806; GA ČR GD310/03/H147
    Institutional research plan: CEZ:AV0Z50200510
    Keywords : macrophage * tnf
    Subject RIV: EE - Microbiology, Virology

    CCF isolated from the coelomic fluid of Eisenia fetida earthworms shows numerous TNF-like activities. CCF-induced membrane depolarization results in macrophage activation and TNF contributes to this activation independently on TNF-receptors

    CCF izolovaný z coelomové tekutiny žížal Eisenia fetida vykazuje řadu vlastností podobných TNF. Depolarizace membrány indukovaná CCF vede k aktivaci makrofágů a TNF k této aktivaci přispívá cestou nezávislou na TNF receptorech
    Permanent Link: http://hdl.handle.net/11104/0140183

     
     
Number of the records: 1  

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