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N6-Methyl-AMP aminohydrolase activates N6-substituted purine acyclic nucleoside phosphonates

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    0044422 - ÚOCHB 2007 RIV US eng J - Journal Article
    Schinkmanová, Markéta - Votruba, Ivan - Holý, Antonín
    N6-Methyl-AMP aminohydrolase activates N6-substituted purine acyclic nucleoside phosphonates.
    [N6-Methyl-AMP aminohydrolasa aktivuje N6-substituované purinové acyklické nukleosidfosfonáty.]
    Biochemical Pharmacology. Roč. 71, č. 9 (2006), s. 1370-1376. ISSN 0006-2952. E-ISSN 1873-2968
    R&D Projects: GA AV ČR(CZ) 1QS400550501
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : N6-methyl-AMP aminohydrolase * me-AMP * cypr-PMEDAP * PMEG
    Subject RIV: CC - Organic Chemistry
    Impact factor: 3.581, year: 2006

    Identification and characterization of a new enzyme, N6-methyl-AMP aminohydrolase, that is responsible for the intracellular activation of N6-cypr-PMEDAP and another N6-substituted purine nucleotide analogs.

    Identifikace a charakterizace nového enzymu, N6-methyl-AMP-aminohydrolasy, který odpovídá za intracelulární aktivaci N6-cypr-PMEDAP a dalších N6-substituovaných purinových analogů nukleotidů.
    Permanent Link: http://hdl.handle.net/11104/0137201

     
     
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