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Different roles of peptidic spacers in proteolytically and hydrolytically cleavable HPMA-based polymeric prodrugs

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    0027133 - MBÚ 2006 RIV SIGLE US eng C - Conference Paper (international conference)
    Hovorka, Ondřej - Císlerová, Lucie - Strohalm, Jiří - Šubr, Vladimír - Ulbrich, Karel - Říhová, Blanka
    Different roles of peptidic spacers in proteolytically and hydrolytically cleavable HPMA-based polymeric prodrugs.
    [Různé role peptidových spojek u proteolyticky a hydrolyticky štěpitelných polymerních proléčiv založených na HPMA.]
    International Nanomedicine and Drug Delivery Symposium /3./. Baltimore, 2005, s. 85-85.
    [International Nanomedicine and Drug Delivery Symposium /3./. Baltimore (US), 26.09.2005-27.09.2005]
    R&D Projects: GA ČR GA305/05/2268; GA ČR GA204/05/2255
    Institutional research plan: CEZ:AV0Z50200510
    Keywords : hpma * polymeric prodrugs
    Subject RIV: EE - Microbiology, Virology

    Polymeric conjugates based on N-(2-hydroxypropyl)methacrylamide (HPMA) have been tested as potential carriers for anticancer drugs, e.g. doxorubicin

    Polymerní konjugáty založené na N-(2-hydroxypropyl)methacrylamidu (HPMA) byly testovány jako potenciální nosiče protinádorových léčiv, např. doxorubicinu
    Permanent Link: http://hdl.handle.net/11104/0117259

     
     
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