0024036 - ÚFCH JH 2006 RIV IE eng J - Journal Article
Sýkora, Jan - Jurkiewicz, P. - Epand, R. M. - Kraayenhof, R. - Langner, M. - Hof, Martin
Influence of the curvature on the water structure in the headgroup region of phospholipid bilayer studied by the solvent relaxation technique.
[Vliv zakřivení na struktuře vody ve fosfolipidové dvouvrstvě studovaný metodou uvolnění rozpouštědla.]
Chemistry and Physics of Lipids. Roč. 135, č. 2 (2005), s. 213-221. ISSN 0009-3084. E-ISSN 1873-2941
R&D Projects: GA AV ČR IAA400400503; GA ČR GA203/05/2308
Institutional research plan: CEZ:AV0Z40400503
Keywords : patman * prodan * coumarin * bound water
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 2.351, year: 2005

Solvent relaxation (SR) in 1,2-dioleoyl-palmitoyl-sn-glycero-3-phosphocholine (DOPC) unilamellar vesicles of different size was probed by 6-hexadecanoyl-2-(((2-(trimethylammonium)ethyl)methyl)amino)naphthalene chloride (Patman), 6-propionyl-2-dimethylaminonaphthalene (Prodan) and 4-[(n-dodecylthio)methyl]-7-(NN-dimethylamino)-coumarin (DTMAC). Patman probes the amount and mobility of the bound water molecules located at the carbonyl region of the bilayer. Membrane curvature significantly accelerates the solvent relaxation process, but does not influence the total Stokes shift, showing that membrane curvature increases the mobility, without affecting the amount of water molecules present in the headgroup region. This pattern was also verified for other phosphatidylcholines.

V této práci byl studován vliv zakřivení na struktuře vody ve fosfolipidové dvouvrstvě studovaný metodou uvolnění rozpouštědla.
Permanent Link: http://hdl.handle.net/11104/0114645