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0535601 - BC 2021 RIV GB eng J - Journal Article
Alghamdi, A.H. - Munday, J.C. - Campagnaro, G.D. - Gurvic, D. - Svensson, F. - Okpara, C.E. - Kumar, A. - Quintana, J. - Abril, M.E.M. - Milic, P. - Watson, L. - Paape, D. - Settimo, L. - Dimitriou, A. - Wielinska, J. - Smart, G. - Anderson, L.F. - Woodley, C.M. - Kelly, S.P.Y. - Ibrahim, H.M.S. - Hulpia, F. - Al-Salabi, M. - Eze, Anthonius A. - Sprenger, T. - Teka, I.A. - Gudin, S. - Weyand, S. - Field, Mark Christian - Dardonville, C. - Tidwell, R.R. - Carrington, M. - O'Neill, P. - Boykin, D.W. - Zachariae, Ul. - de Koning, H.P.
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei.
eLife. Roč. 9, AUG 11 2020 (2020), č. článku e56416. ISSN 2050-084X. E-ISSN 2050-084X
Institutional support: RVO:60077344
Keywords : substrate recognition motifs * high-affinity transporter * blood-stream forms * cross-resistance * drug-resistance * nucleoside transporter * adenosine transporter * diminazene aceturate * aquaglyceroporin 2 * diamidine drugs
OECD category: Microbiology
Impact factor: 8.146, year: 2020
Method of publishing: Open access
https://elifesciences.org/articles/56416
Permanent Link: http://hdl.handle.net/11104/0313576