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0540776 - BC 2021 RIV US eng J - Journal Article
Zoltner, M. - Campagnaro, G.D. - Taleva, Gergana - Burrell, A. - Cerone, M. - Leung, K.-F. - Achcar, F. - Horn, D. - Vaughan, S. - Gadelha, C. - Zíková, Alena - Barrett, M.P. - de Koning, H.P. - Field, Mark Christian
Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes.
Journal of Biological Chemistry. Roč. 295, č. 24 (2020), s. 8331-8347. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR GA17-22248S; GA MŠMT(CZ) EF16_019/0000759
EU Projects: Wellcome Trust(GB) 204697/Z/16/Z
Institutional support: RVO:60077344
Keywords : trypanocidal drug suramin * web-based tool * proline metabolism * mass-spectrometry * brucei * identification * membrane * resistance * inhibitors * expression * drug action * trypanosome * Trypanosoma brucei * parasite metabolism * metabolomics * suramin * glycosomes * polypharmacology * proteomics * differentiation * drug mechanisms * energy homeostasis * sleeping sickness
OECD category: Microbiology
Impact factor: 5.157, year: 2020
Method of publishing: Open access
https://www.jbc.org/article/S0021-9258(17)49420-8/pdf
Permanent Link: http://hdl.handle.net/11104/0318378