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  1. 1.
    0048758 - ÚOCHB 2007 RIV DK eng J - Journal Article
    Whittingham, J. L. - Youshang, Z. - Žáková, Lenka - Dodson, E. J. - Turkenburg, J. P. - Brange, J. - Dodson, G. G.
    I222 crystal form of despentapeptide (B26-B30) insulin provides new insights into the properties of monomeric insulin.
    [I222 krystalová forma despentapeptid (B26-B30) insulinu podává nové informace o vlastnostech monomerního insulinu.]
    Acta Crystallographica Section D-Biological Crystallography. Roč. 62, č. 5 (2006), s. 505-511. ISSN 0907-4449
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : insulin * crystal structure * monomer * despentapeptid
    Subject RIV: CE - Biochemistry
    Impact factor: 1.687, year: 2006
    Permanent Link: http://hdl.handle.net/11104/0003778
     
     
  2. 2.
    0342433 - ÚOCHB 2011 RIV US eng J - Journal Article
    Jiráček, Jiří - Žáková, Lenka - Antolíková, Emília - Watson, C. J. - Turkenburg, J. P. - Dodson, G. G. - Brzozowski, A. M.
    Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues.
    Proceedings of the National Academy of Sciences of the United States of America. Roč. 107, č. 5 (2010), s. 1966-1970. ISSN 0027-8424. E-ISSN 1091-6490
    R&D Projects: GA MŠMT(CZ) LC06077; GA AV ČR KJB400550702
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : insulin * analogue * conformation * beta-turn * N-methylation
    Subject RIV: CC - Organic Chemistry
    Impact factor: 9.771, year: 2010
    Permanent Link: http://hdl.handle.net/11104/0185172
     
     
  3. 3.
    0366020 - ÚOCHB 2012 RIV US eng J - Journal Article
    Antolíková, Emília - Žáková, Lenka - Turkenburg, J. P. - Watson, C. J. - Hančlová, Ivona - Šanda, Miloslav - Cooper, A. - Kraus, Tomáš - Brzozowski, A. M. - Jiráček, Jiří
    Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface.
    Journal of Biological Chemistry. Roč. 286, č. 42 (2011), s. 36968-36977. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA MŠMT(CZ) LC06077
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : insulin * dimer * analog
    Subject RIV: CC - Organic Chemistry
    Impact factor: 4.773, year: 2011
    Permanent Link: http://hdl.handle.net/11104/0201123
     
     
  4. 4.
    0392749 - ÚOCHB 2014 RIV US eng J - Journal Article
    Žáková, Lenka - Kletvíková, Emília - Veverka, Václav - Lepšík, Martin - Watson, C. J. - Turkenburg, J. P. - Jiráček, Jiří - Brzozowski, A. M.
    Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality.
    Journal of Biological Chemistry. Roč. 288, č. 15 (2013), s. 10230-10240. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA ČR GPP207/11/P430; GA MŠMT(CZ) LK11205
    Institutional support: RVO:61388963
    Keywords : insulin * insulin receptor * structure * NMR
    Subject RIV: CE - Biochemistry
    Impact factor: 4.600, year: 2013
    Permanent Link: http://hdl.handle.net/11104/0221560
     
     
  5. 5.
    0429661 - ÚOCHB 2015 RIV US eng J - Journal Article
    Kosinová, Lucie - Veverka, Václav - Novotná, P. - Collinsová, Michaela - Urbanová, M. - Moody, N. R. - Turkenburg, J. P. - Jiráček, Jiří - Brzozowski, A. M. - Žáková, Lenka
    Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin.
    Biochemistry. Roč. 53, č. 21 (2014), s. 3392-3402. ISSN 0006-2960
    R&D Projects: GA ČR GPP207/11/P430; GA ČR GAP208/11/0105; GA MŠMT(CZ) LK11205
    Institutional support: RVO:61388963
    Keywords : insulin * structure * N-terminus * B-chain * T/R transition
    Subject RIV: CE - Biochemistry
    Impact factor: 3.015, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0234773
     
     
  6. 6.
    0435229 - ÚOCHB 2015 RIV US eng J - Journal Article
    Žáková, Lenka - Kletvíková, Emília - Lepšík, Martin - Collinsová, Michaela - Watson, C. J. - Turkenburg, J. P. - Jiráček, Jiří - Brzozowski, A. M.
    Human insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex.
    Acta Crystallographica Section D-Biological Crystallography. Roč. 70, č. 10 (2014), s. 2765-2774. ISSN 0907-4449
    R&D Projects: GA ČR GPP207/11/P430; GA ČR GBP208/12/G016
    Institutional support: RVO:61388963
    Keywords : insulin * insulin receptor * complex * active form * analog * structure
    Subject RIV: CE - Biochemistry
    Impact factor: 7.232, year: 2013
    Permanent Link: http://hdl.handle.net/11104/0239539
     
     
  7. 7.
    0458657 - ÚOCHB 2017 RIV GB eng J - Journal Article
    Viková, Jitka - Collinsová, Michaela - Kletvíková, Emília - Buděšínský, Miloš - Kaplan, V. - Žáková, Lenka - Veverka, Václav - Hexnerová, Rozálie - Tarazona Avinó, R. J. - Straková, Jana - Selicharová, Irena - Vaněk, Václav - Wright, D. W. - Watson, C. J. - Turkenburg, J. P. - Brzozowski, A. M. - Jiráček, Jiří
    Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
    Scientific Reports. Roč. 6, Jan 21 (2016), č. článku 19431. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA MŠMT(CZ) LK11205; GA MŠMT(CZ) LO1304
    Institutional support: RVO:61388963
    Keywords : insulin * insulin receptor * diabetes * protein design * protein synthesis
    Subject RIV: CE - Biochemistry
    Impact factor: 4.259, year: 2016
    http://www.nature.com/articles/srep19431
    Permanent Link: http://hdl.handle.net/11104/0258905
    FileDownloadSizeCommentaryVersionAccess
    0458657.pdf52.4 MBPublisher’s postprintopen-access
     
     
  8. 8.
    0470039 - BTÚ 2017 RIV GB eng J - Journal Article
    Agirre, J. - Ariza, A. - Offen, W. A. - Turkenburg, J. P. - Roberts, S. M. - McNicholas, S. - Harris, P. V. - McBrayer, B. - Dohnálek, Jan - Cowtan, K. D. - Davies, G. J. - Wilson, K. S.
    Three-dimensional structures of two heavily N-glycosylated Aspergillus sp family GH3 beta-D-glucosidases.
    Acta Crystallographica Section D-Structural Biology. Roč. 72, č. 2 (2016), s. 254-265. ISSN 2059-7983. E-ISSN 2059-7983
    R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:86652036
    Keywords : cellulose degradation * N-glycan * biofuels * glycoblocks
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 2.114, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0267784
     
     
  9. 9.
    0476143 - ÚOCHB 2018 RIV US eng J - Journal Article
    Palivec, Vladimír - Viola, C. M. - Kozak, M. - Ganderton, T. R. - Křížková, Květoslava - Turkenburg, J. P. - Halušková, Petra - Žáková, Lenka - Jiráček, Jiří - Jungwirth, Pavel - Brzozowski, A. M.
    Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
    Journal of Biological Chemistry. Roč. 292, č. 20 (2017), s. 8342-8355. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA ČR(CZ) GA16-01074S
    Institutional support: RVO:61388963
    Keywords : insulin * serotonin * dopamine * molecular dynamics * crystallography * spectroscopy
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.011, year: 2017
    http://www.jbc.org/content/292/20/8342.full
    Permanent Link: http://hdl.handle.net/11104/0272675
     
     
  10. 10.
    0533335 - ÚOCHB 2021 RIV GB eng J - Journal Article
    Dzianová, P. - Asai, Seiya - Chrudinová, Martina - Kosinová, L. - Potalitsyn, Pavlo - Šácha, Pavel - Hadravová, Romana - Selicharová, Irena - Kříž, J. - Turkenburg, J. P. - Brzozowski, A. M. - Jiráček, Jiří - Žáková, Lenka
    The efficiency of insulin production and its content in insulin-expressing model β-cells correlate with their Zn2+ levels.
    Open Biology. Roč. 10, č. 10 (2020), č. článku 200137. E-ISSN 2046-2441
    R&D Projects: GA MŠMT(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : insulin * zinc * beta cells * production ZnT8
    OECD category: Biochemistry and molecular biology
    Impact factor: 6.411, year: 2020
    Method of publishing: Open access
    https://doi.org/10.1098/rsob.200137
    Permanent Link: http://hdl.handle.net/11104/0311840
     
     

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