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  1. 1.
    0533326 - MBÚ 2021 RIV US eng J - Journal Article
    Osičková, Adriana - Khaliq, Humaira - Mašín, Jiří - Jurnečka, David - Suková, Anna - Fišer, Radovan - Holubová, Jana - Staněk, Ondřej - Šebo, Peter - Osička, Radim
    Acyltransferase-mediated selection of the length of the fatty acyl chain and of the acylation site governs activation of bacterial RTX toxins.
    Journal of Biological Chemistry. Roč. 295, č. 28 (2020), s. 9268-9280. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA MŠMT(CZ) LM2018127
    Institutional support: RVO:61388971
    Keywords : acylation * acyltransferase * cytotoxicit
    OECD category: Microbiology
    Impact factor: 5.157, year: 2020
    Method of publishing: Open access
    Permanent Link: http://hdl.handle.net/11104/0311734
     
     
  2. 2.
    0536763 - MBÚ 2021 RIV CH eng J - Journal Article
    Rahman, Waheed Ur - Osičková, Adriana - Klímová, Nela - Lora, J. - Balashova, N. - Osička, Radim
    Binding of Kingella kingae RtxA Toxin Depends on Cell Surface Oligosaccharides, but Not on beta(2) Integrins.
    International Journal of Molecular Sciences. Roč. 21, č. 23 (2020), č. článku 9092. E-ISSN 1422-0067
    R&D Projects: GA ČR(CZ) GA18-18079S; GA MŠMT(CZ) LM2018133
    Institutional support: RVO:61388971
    Keywords : integrins * Kingella kingae * oligosaccharides
    OECD category: Microbiology
    Impact factor: 5.924, year: 2020
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/21/23/9092
    Permanent Link: http://hdl.handle.net/11104/0314511
     
     
  3. 3.
    0547494 - MBÚ 2022 RIV CH eng J - Journal Article
    Malandra, Anna - Rahman, Waheed Ur - Klímová, Nela - Streparola, Gaia - Holubová, Jana - Osičková, Adriana - Bariselli, S. - Šebo, Peter - Osička, Radim
    Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein.
    International Journal of Molecular Sciences. Roč. 22, č. 16 (2021), č. článku 9064. E-ISSN 1422-0067
    R&D Projects: GA ČR(CZ) GA19-12695S; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LM2018133; GA MŠMT EF18_046/0015861
    Research Infrastructure: CCP II - 90126
    Institutional support: RVO:61388971
    Keywords : adenylate cyclase toxin * Bordetella * cAMP * creb * epithelium * mucin * pertussis toxin
    OECD category: Microbiology
    Impact factor: 6.208, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/22/16/9064
    Permanent Link: http://hdl.handle.net/11104/0323707
     
     
  4. 4.
    0547497 - MBÚ 2022 RIV DE eng J - Journal Article
    Lepesheva, Anna - Osičková, Adriana - Holubová, Jana - Jurnečka, David - Knoblochová, Šárka - Espinosa-Vinals, Carlos Angel - Bumba, Ladislav - Škopová, Karolína - Fišer, Radovan - Osička, Radim - Šebo, Peter - Mašín, Jiří
    Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins.
    Scientific Reports. Roč. 11, č. 1 (2021), č. článku 19814. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA MŠMT(CZ) LM2018133; GA ČR(CZ) GA19-12695S; GA ČR(CZ) GX19-27630X; GA ČR(CZ) GA19-04607S
    Research Infrastructure: CIISB II - 90127
    Institutional support: RVO:61388971
    Keywords : adenylate-cyclase toxin * escherichia-coli hemolysin * bordetella-pertussis cyaa * cell-invasive activity * alpha-hemolysin * membrane translocation * complement receptor-3 * fatty-acylation * calcium * binding
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.997, year: 2021
    Method of publishing: Open access
    https://www.nature.com/articles/s41598-021-99112-3
    Permanent Link: http://hdl.handle.net/11104/0323712
     
     
  5. 5.
    0549727 - MBÚ 2022 RIV CH eng J - Journal Article
    Holubová, Jana - Juhasz, Attila - Mašín, Jiří - Staněk, Ondřej - Jurnečka, David - Osičková, Adriana - Šebo, Peter - Osička, Radim
    Selective enhancement of the cell-permeabilizing activity of adenylate cyclase toxin does not increase virulence of bordetella pertussis.
    International Journal of Molecular Sciences. Roč. 22, č. 21 (2021), č. článku 11655. E-ISSN 1422-0067
    R&D Projects: GA MŠMT(CZ) LM2018133; GA ČR(CZ) GA19-12695S
    Research Infrastructure: CIISB II - 90127; CCP II - 90126
    Institutional support: RVO:61388971
    Keywords : Adenylate cyclase toxin * Bordetella pertussis * CAMP intoxication * Lung colonization * Lung inflammation * Pore-forming activity * RTX toxin * Virulence
    OECD category: Microbiology
    Impact factor: 6.208, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/22/21/11655
    Permanent Link: http://hdl.handle.net/11104/0325678
     
     
  6. 6.
    0556379 - MBÚ 2023 RIV CH eng J - Journal Article
    Filipi, Kateřina - Rahman, Waheed Ur - Osičková, Adriana - Osička, Radim
    Kingella kingae RtxA Cytotoxin in the Context of Other RTX Toxins.
    Microorganisms. Roč. 10, č. 3 (2022), č. článku 518. E-ISSN 2076-2607
    R&D Projects: GA ČR(CZ) GA22-15825S
    Institutional support: RVO:61388971
    Keywords : escherichia-coli-hemolysin * adenylate-cyclase toxin * aggregatibacter-actinomycetemcomitans leukotoxin * pasteurella-haemolytica leukotoxin * real-time pcr * polymerase-chain-reaction * outer-membrane vesicles * bordetella-pertussis cyaa * terminal secretion signal * cell-invasive activity * beta(2) integrins * Kingella kingae * membrane * pore-forming * RtxA * RTX toxin
    OECD category: Microbiology
    Impact factor: 4.5, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/2076-2607/10/3/518
    Permanent Link: http://hdl.handle.net/11104/0331349
     
     
  7. 7.
    0562903 - MBÚ 2023 RIV CH eng J - Journal Article
    Golshani, Maryam - Rahman, Waheed Ur - Osičková, Adriana - Holubová, Jana - Lora, J. - Balashova, N. - Šebo, Peter - Osička, Radim
    Filamentous Hemagglutinin of Bordetella pertussis Does Not Interact with the β2 Integrin CD11b/CD18.
    International Journal of Molecular Sciences. Roč. 23, č. 20 (2022), č. článku 12598. E-ISSN 1422-0067
    R&D Projects: GA MŠMT(CZ) LM2018133; GA MŠMT(CZ) LX22NPO5103
    Institutional support: RVO:61388971
    Keywords : adenylate cyclase toxin * Bordetella pertussis * CD11b/CD18 * filamentous hemagglutinin * heparin * integrin
    OECD category: Microbiology
    Impact factor: 5.6, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/23/20/12598
    Permanent Link: https://hdl.handle.net/11104/0335072
    FileDownloadSizeCommentaryVersionAccess
    Filamentous Hemagglutinin.pdf04.2 MBPublisher’s postprintopen-access
     
     
  8. 8.
    0573968 - MBÚ 2024 RIV NL eng J - Journal Article
    Osičková, Adriana - Knoblochová, Šárka - Bumba, Ladislav - Man, Petr - Kalaninová, Zuzana - Lepesheva, Anna - Jurnečka, David - Čížková, Monika - Biedermannová, Lada - Goldsmith, J. A. - Maynard, J. A. - McLellan, J. S. - Osička, Radim - Šebo, Peter - Mašín, Jiří
    A conserved tryptophan in the acylated segment of RTX toxins controls their βinf2/inf integrin–independent cell penetration.
    Journal of Biological Chemistry. Roč. 299, č. 8 (2023), č. článku 104978. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA ČR(CZ) GA22-01558S; GA ČR(CZ) GA22-01558S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EF18_046/0015974; GA ČR(CZ) GX19-27630X
    Research Infrastructure: e-INFRA CZ - 90140; EATRIS-CZ IV - 90253; CIISB III - 90242
    Institutional support: RVO:61388971 ; RVO:86652036
    Keywords : acylated segment * adenylate cyclase toxin * cytotoxicity * hydrogen/deuterium exchange * RTX toxin * thermal stability * tryptophan residue * α-hemolysin * β integrins 2
    OECD category: Microbiology
    Impact factor: 4.8, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0021925823020069?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0344352
     
     
  9. 9.
    0579872 - ÚMG 2024 RIV GB eng J - Journal Article
    Gruper, Y. - Wolff, A. S. B. - Glanz, L. - Špoutil, František - Marthinussen, M. C. - Osičková, Adriana - Herzig, Y. - Goldfarb, Y. - Aranaz-Novaliches, Gorreti - Dobeš, J. - Kadouri, N. - Ben-Nun, O. - Binyamin, A. - Lavi, B. - Givony, T. - Khalaila, R. - Gome, T. - Wald, Tomáš - Mrázková, Blanka - Sochen, C. - Besnard, M. - Ben-Dor, S. - Feldmesser, E. - Orlova, E. M. - Hegedus, C. - Lampe, I. - Papp, T. - Felszeghy, S. - Sedláček, Radislav - Davidovich, E. - Tal, N. - Shouval, D. S. - Shamir, R. - Guillonneau, C. - Szondy, Z. - Lundin, K. E. A. - Osička, Radim - Procházka, Jan - Husebye, E. S. - Abramson, J.
    Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease.
    Nature. Roč. 624, č. 7992 (2023), s. 653-662. ISSN 0028-0836. E-ISSN 1476-4687
    R&D Projects: GA MŠMT(CZ) LM2023053; GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA ČR GJ19-19025Y; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045
    Institutional support: RVO:68378050 ; RVO:61388971
    Keywords : antibody * enamel * immune response * protein * tolerance * tooth
    OECD category: Biochemistry and molecular biology; Immunology (MBU-M)
    Impact factor: 64.8, year: 2022
    Method of publishing: Limited access
    https://www.nature.com/articles/s41586-023-06776-0
    Permanent Link: https://hdl.handle.net/11104/0348991
     
     
  10. 10.
    0585467 - MBÚ 2025 RIV NL eng J - Journal Article
    Lepesheva, Anna - Grobarčíková, Michaela - Osičková, Adriana - Jurnečka, David - Knoblochová, Šárka - Čížková, Monika - Osička, Radim - Šebo, Peter - Mašín, Jiří
    Modification of the RTX domain cap by acyl chains of adapted length rules the formation of functional hemolysin pores.
    Biochimica Et Biophysica Acta-Biomembranes. Roč. 1866, č. 5 (2024), s. 184311. ISSN 0005-2736. E-ISSN 1879-2642
    R&D Projects: GA ČR(CZ) GA22-15825S; GA ČR(CZ) GA22-01558S; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EH22_008/0004597
    Research Infrastructure: EATRIS-CZ IV - 90253; CIISB III - 90242
    Institutional support: RVO:61388971
    Keywords : RTX toxin * Adenylate cyclase toxin * α-Hemolysin * Chimera * Fatty acylation * Cytotoxicity
    OECD category: Microbiology
    Impact factor: 3.4, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0005273624000427?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0353157
    FileDownloadSizeCommentaryVersionAccess
    Modification of the RTX.pdf03 MBPublisher’s postprintopen-access
     
     

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