Vet Med - Czech, 2022, 67(2):99-104 | DOI: 10.17221/55/2021-VETMED

Benign ovarian teratoma in the dog with predominantly nervous tissue: A case reportCase Report

P Makovicky1, AV Makarevich2, P Makovicky3, A Seidavi4, L Vannucci5, K Rimarova6
1 Infectious Diseases and Preventive Medicine, Veterinary Research Institute, v. v. i., Brno, Czech Republic
2 National Agricultural and Food Centre, Research Institute for Animal Production, Lužianky, Slovak Republic
3 Department of Biology, Faculty of Education, J. Selye University, Komárno, Slovak Republic
4 Department of Animal Science, Rasht Branch, Islamic Azad University, Rasht, Iran
5 Laboratory of Immunotherapy, Institute of Microbiology of the Czech Academy of Sciences, v. v. i., Prague, Czech Republic
6 Department of Public Health and Hygiene, Faculty of Medicine, P. J. Šafárik University, Košice, Slovak republic

Ovarian teratomas are rare neoplasms in female dogs, and they are characterised by the proliferation of tissues of embryonic origin. Most teratomas are benign, but a histological diagnosis is important for clinicians. The objective of this article is to describe a benign ovarian teratoma in a dog, which was found on the street and was appearing like pregnant. A veterinary inspection by palpation documented an enlarged abdomen with a mass of tough matter located on the right side in the abdominal-pelvic part. An ultrasound examination presumed neoplastic mass in region of ovary. A bilateral ovariohysterectomy was performed and the subsequent histological evaluation revealed a benign ovarian teratoma with a histochemically and immunohistochemically verified nervous tissue. After one year, no distant metastases were found and the dog was recognised as being clinically healthy without problems. On the basis of the ultrasonography diagnostics and histopathological analyses, we have demonstrated the occurrence of a benign ovarian teratoma in a dog.

Keywords: germ cell neoplasm; ovary; veterinary pathology

Received: April 14, 2021; Accepted: September 22, 2021; Published: February 15, 2022  Show citation

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Makovicky P, Makarevich A, Makovicky P, Seidavi A, Vannucci L, Rimarova K. Benign ovarian teratoma in the dog with predominantly nervous tissue: A case report. Vet Med-Czech. 2022;67(2):99-104. doi: 10.17221/55/2021-VETMED.
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References

  1. Akbulut M, Kelten EC, Ege CB. Mature cystic teratoma with predominantly neurogenic elements - Case report. Aegean Pathol J. 2006 Aug;22(3):18-20.
  2. Blaszak B, Walkowski M, Ibbs M, Jaskowski JM. Teratoma adultum in a bitch: A case report. Vet Med-Czech. 2009 Aug;54(8):379-81. Go to original source...
  3. Chai Y, Woo CG, Kim JY, Kim CJ, Khang SK, Kim J, Park IA, Kim EN, Kim KR. Diagnostic significance of cellular neuroglial tissue in ovarian immature teratoma. J Pathol Transl Med. 2017 Jan;51(1):49-55. Go to original source... Go to PubMed...
  4. Coggeshall JD, Franks JN, Wilson DU, Wiley JP. Primary ovarian teratoma and GCT with intra-abdominal metastasis in a dog. J Am Anim Hosp Assoc. 2012 Nov-Dec;48 (6):424-8. Go to original source... Go to PubMed...
  5. Da Costa DA, Da Silva MRM, De Souza NF, Pereira WLA, Cardoso AMC. Giant canine ovarian teratoma: Case report. J Cytol Histol. 2017 Aug;8(3):1-3. Go to original source...
  6. De Bosschere H, Durnez V, Ducatelle R. Malignant ovarian teratoma in a Golden Retriever. Vlaams Diergeneesk Tijdcchr. 1999 Feb;68(2):96-100.
  7. Gulcubuk A, Altun ED, Bozkurt ER, Sontas BS, Haktanir D. Ovarian teratoma in a dog. Turkish J Vet Anim Sci. 2012 May;36(5):573-6. Go to original source...
  8. Iemura Y, Yamada Y, Hirata M, Kataoka TR, Minamiguchi S, Haga H. Histopathological characterization of the neuroglial tissue in ovarian teratoma associated with antiN-methyl-d-aspartate (NMDA) receptor encephalitis. Pathol Int. 2018 Dec;68(12):677-84. Go to original source... Go to PubMed...
  9. Linder D, McCaw BK, Hecht F. Parthenogenic origin of benign ovarian teratomas. N Engl J Med. 1975 Jan 9;292 (2):63-6. Go to original source... Go to PubMed...
  10. Lopez D, Singh A, Wright TF, Gartley C, Walker M. Single incision laparoscopic-assisted ovariohysterectomy for an ovarian tumour in a dog. Can Vet J. 2017 Sep;58(9): 975-9.
  11. Makovicky P, Svecova I. Veterinary pathology: The past, present and the future. Phenogenomic Newsletter. 2016 April;2(2):22-3.
  12. Nagashima Y, Hoshi K, Tanaka R, Shibazaki A, Fujiwara K, Konno K, Machida N, Yamane Y. Ovarian and retroperitoneal teratomas in a dog. J Vet Med Sci. 2000 Jul;62 (7):793-5. Go to original source... Go to PubMed...
  13. Oviedo-Penata CA, Hincapie L, Benavides CR, Maldonado JG. Concomitant presence of ovarian tumors (teratoma and granulosa cell tumor), and pyometra in an English Bulldog female dog: A case report. Front Vet Sci. 2020 Jan;14(6):500. Go to original source... Go to PubMed...
  14. Patnaik AK, Greenlee PG. Canine ovarian neoplasms: A clinic-pathologic study of 71 cases, including histology of 12 granulosa cell tumors. Vet Pathol. 1987 Nov;24(6): 509-14. Go to original source... Go to PubMed...
  15. Pegas GRA, Monteiro LN, Cassali GD. Extragonadal malignant teratoma in a dog - Case report. Arq Bras Med Vet Zootec. 2020 Jan-Feb;72(1):115-8. Go to original source...
  16. Pires MDA, Catarino JC, Vilhena H, Faim S, Neves T, Freire A, Seixas F, Orge L, Payan-Carreira R. Co-existing monophasic teratoma and uterine adenocarcinoma in a female dog. Reprod Domest Anim. 2019 Jul;54(7):1044-9. Go to original source... Go to PubMed...
  17. Rota A, Tursi M, Zabarino S, Appino S. Monophasic teratoma of the ovarian remnant in a bitch. Reprod Domest Anim. 2013 Apr;48(2):26-8. Go to original source... Go to PubMed...
  18. Sarrau S. Iatrogenic ureteral lesion following a bulky ovarian teratoma excision in a 3-year bitch. Rev Veterinaire Clin. 2018 Apr;53(4):115-20.
  19. Stussi A, Bohler A, Zednik T, Shiblz S, Zednik P. Teratoma - A rare ovarian tumour in a bitch. Wien Tierärztl Monatsschr. 2008 Mar;95(3):85-90.
  20. Xiang H, Han J, Ridley WE, Ridley LJ. Canine tooth: Mature cystic teratoma. J Med Imaging Radiat Oncol. 2018 Oct; 62(S1):61. Go to original source... Go to PubMed...
  21. Yamaguchi Y, Sato T, Shibuya H, Tsumagari S, Suzuki T. Ovarian teratoma with a formed lens and non-supportive inflammation in an old dog. J Vet Med Sci. 2004 Jul;66(7): 861-4. Go to original source... Go to PubMed...
  22. Yoshimura, Yamamoto M, Moriya M, Endo T, Sugiura N, Kato T, Matsuda Y, Ishiwata T, Kajigaya H, Kamiiya S. Teratoma of the ovary in a free-ranging Japanese Raccoon dog (Nyctereutes Procyonoides Viverrinus). J Zoo Wildl Med. 2017 Mar;48(1):265-8. Go to original source... Go to PubMed...

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