Issue 39, 2023
From the journal:

Organic & Biomolecular Chemistry

Rhodium(ii)-catalyzed transannulation approach to N-fluoroalkylated indoles†

Olga Bakhanovich, ORCID logo ab   Blanka Klepetářováa  and  Petr Beier ORCID logo *a  

* Corresponding authors

a Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague 6, Czech Republic
E-mail: cbeier@uochb.cas.cz

b Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 2030/8, 128 43 Prague, Czech Republic

Abstract

Copper(I)-catalyzed cycloaddition of substituted cyclohexenyl acetylenes with azido(per)fluoroalkanes afforded 4-cyclohexenyl-substituted N-(per)fluoroalkylated 1,2,3-triazoles. Their rhodium(II)-catalyzed transannulation led to fused N-(per)fluoroalkyl pyrroles and subsequent oxidation provided N-(per)fluoroalkyl indoles.

Graphical abstract: Rhodium(ii)-catalyzed transannulation approach to N-fluoroalkylated indoles

About
Cited by
Related
Download options Please wait...

Associated articles

Supplementary files

Article information

DOI
https://doi.org/10.1039/D3OB01415K
Article type
Paper
Submitted
04 Sep 2023
Accepted
20 Sep 2023
First published
21 Sep 2023
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2023,21, 7924-7927

Permissions

Request permissions

Rhodium(II)-catalyzed transannulation approach to N-fluoroalkylated indoles

O. Bakhanovich, B. Klepetářová and P. Beier, Org. Biomol. Chem., 2023, 21, 7924 DOI: 10.1039/D3OB01415K

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements