Cent Eur J Public Health 2019, 27(4):305-311 | DOI: 10.21101/cejph.a5475

Relation between personal exposure and outdoor concentrations of carcinogenic polycyclic aromatic hydrocarbons during smog episode

Vlasta ©vecová1, Jan Topinka1, Ivo Solanský1, David Broday2, Radim J. ©rám1
1 Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic
2 Technion Centre of Excellence in Exposure Science and Environmental Health, Faculty of Civil and Environmental Engineering, Technion-Israel Institute of Technology, Haifa, Israel

Objectives: To our knowledge this is the first study measuring personal exposure to carcinogenic polycyclic aromatic hydrocarbons (cPAHs) bound to airborne particulate matter ≤ 2.5 µm (PM2.5) in periods of high air pollution (smog episode) in which citizen were tracked.

Methods: Measurements were performed in industrial regions of the Czech Republic: Ostrava, Karviná, Havířov. The city of Prague served as a control. Personal monitoring was conducted by active personal monitors for 48 hours. Non-smoking city policemen from Prague, Karviná and Havířov, office workers from Ostrava city and volunteers from Ostrava-Radvanice and Bartovice participated in the study (N = 214).

Results: The average personal exposure to benzo[a]pyrene (B[a]P) was highest in Ostrava (17.2 ng/m3), followed by Karviná, Havířov, Radvanice and Bartovice, and Prague (14.2, 12.0, 9.3, and 2.8 ng/m3, respectively). We tested for association between the personal exposure to cPAHs and various health-related factors extracted from the questionnaires, including lifestyle factors and day-to-day activities.

Conclusions: Exposure to outdoor cPAHs, environmental tobacco smoke (ETS), commuting, and time spent indoors (in restaurants, workplace or home) were found to be the main determinants of the personal exposure. Daily cPAHs measurements in highly polluted areas are needed for evaluating the personal exposure and to avoid its underestimation resulting from stationary monitoring.

Keywords: personal monitoring, personal exposure, air pollution, PM2.5, benzo[a]pyrene, smog

Received: August 2, 2018; Revised: October 14, 2019; Accepted: October 14, 2019; Published: December 31, 2019  Show citation

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©vecová V, Topinka J, Solanský I, Broday D, ©rám RJ. Relation between personal exposure and outdoor concentrations of carcinogenic polycyclic aromatic hydrocarbons during smog episode. Cent Eur J Public Health. 2019;27(4):305-311. doi: 10.21101/cejph.a5475. PubMed PMID: 31951690.
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    References

    1. Air quality in Europe - 2017 report [Internet]. Luxembourg: European Environmental Agency; 2017 [cited 2018 March 9]. Available from: https://www.eea.europa.eu//publications/air-quality-in-europe-2017.
    2. Tomáąková H, Tomáąek I, ©lachtová H, ©ebáková H. Impact assessment of PM10 concentrations on mortality and morbidity in Ostrava during smog episodes. Hygiena. 2011;56(1):5-10. (In Czech.)
    3. World Health Organization. Ambient (outdoor) air quality and health [Internet]. 2018 [cited 2018 July 12]. Available from: http://www.who.int/mediacentre/factsheets/fs313/en.
    4. Puklová V, Lustigová M, Kazmarová H, Kotlík B. Towards the effects of airborne pollution on mortality-rates in the Czech Republic. Hygiena. 2013;58(1):5-10. (In Czech.) Go to original source...
    5. Dostal M, Pastorkova A, Rychlik S, Rychlikova E, Svecova V, Schallerova E, et al. Comparison of child morbidity in regions of Ostrava, Czech Republic, with different degrees of pollution: a retrospective cohort study. Environ Health. 2013 Sep 3;12(1):74. doi: 10.1186/1476-069X-12-74. Go to original source... Go to PubMed...
    6. World Health Organization, International Agency for Research on Cancer. Monographs on the Evaluation of Carcinogenic Risks to Humans [Internet]. 2018 [cited 2018 Jul 10]. Available from: http://monographs.iarc.fr/ENG/Classification/index.php.
    7. Widziewicz K, Rogula-Kozłowska W, Loska K, Kociszewska K, Majewski G. Health Risk Impacts of Exposure to Airborne Metals and Benzo(a)Pyrene during Episodes of High PM10 Concentrations in Poland. Biomed Environ Sci. 2018;31(1):23-36.
    8. Ghosh R, Rossner P, Honkova K, Dostal M, Sram RJ, Hertz-Picciotto I. Air pollution and childhood bronchitis: Interaction with xenobiotic, immune regulatory and DNA repair genes. Environ Int. 2016;87:94-100. Go to original source... Go to PubMed...
    9. Zhu X, Fan ZT, Wu X, Jung KH, Ohman-Strickland P, Bonanno LJ, et al. Ambient concentrations and personal exposure to polycyclic aromatic hydrocarbons (PAH) in an urban community with mixed sources of air pollution. J Expo Sci Environ Epidemiol. 2011;21(5):437-49. Go to original source... Go to PubMed...
    10. Spiezia L, Campello E, Bon M, Maggiolo S, Pelizzaro E, Simioni P. Short-term exposure to high levels of air pollution as a risk factor for acute isolated pulmonary embolism. Thromb Res. 2014;134(2):259-63. Go to original source... Go to PubMed...
    11. Sram RJ, Binkova B, Beskid O, Milcova A, Rossner P, Rossner P Jr, et al. Biomarkers of exposure and effect-interpretation in human risk assessment. Air Qual Atmos Health. 2011;4(3-4):161-7. Go to original source... Go to PubMed...
    12. Rossner P Jr, Rossnerova A, Spatova M, Beskid O, Uhlirova K, Libalova H, et al. Analysis of biomarkers in a Czech population exposed to heavy air pollution. Part II: chromosomal aberrations and oxidative stress. Mutagenesis. 2013 Jan;28(1):97-106. Go to original source... Go to PubMed...
    13. Rossner P Jr, Svecova V, Schmuczerova J, Milcova A, Tabashidze N, Topinka J, et al. Analysis of biomarkers in a Czech population exposed to heavy air pollution. Part I: bulky DNA adducts. Mutagenesis. 2013 Jan;28(1):89-95. Go to original source... Go to PubMed...
    14. Svecova V, Topinka J, Solansky I, Rossner P Jr, Sram RJ. Personal exposure to carcinogenic polycyclic aromatic hydrocarbons in the Czech Republic. J Expo Sci Environ Epidemiol. 2013;23(4):350-5. Go to original source... Go to PubMed...
    15. Sram RJ, Veleminsky M Jr, Veleminsky M Sr, Stejskalova J. The impact of air pollution to central nervous system in children and adults. Neuro Endocrinol Lett. 2017;38(6):389-96. Go to PubMed...
    16. Warburton DER, Bredin SSD, Shellington EM, Cole C, de Faye A, Harris J, et al. A systematic review of the short-term health effects of air pollution in persons living with coronary heart disease. J Clin Med. 2019 Feb 24;8(2): pii: E274. Go to original source... Go to PubMed...
    17. Wu Y, Li M, Tian Y, Cao Y, Song J, Huang Z, et al. Short-term effects of ambient fine particulate air pollution on inpatient visits for myocardial infarction in Beijing, China. Environ Sci Pollut Res Int. 2019;26(14):14178-83. Go to original source... Go to PubMed...
    18. Svecova V, Topinka J, Solansky I, Sram RJ. Personal exposure to volatile organic compounds in the Czech Republic. J Expo Sci Environ Epidemiol. 2012;22(5):455-60. Go to original source... Go to PubMed...
    19. Langone JJ, Van Vunakis H. Radioimmunoassay of nicotine, cotinine, and gamma-(3-pyridyl)-gamma-oxo-N-methylbutyramide. Methods Enzymol. 1982;84:628-40. Go to original source... Go to PubMed...
    20. Williams RW, Watts RR, Stevens RK, Stone CL, Lewtas J. Evaluation of a personal air sampler for twenty-four hour collection of fine particles and semivolatile organics. J Expo Anal Environ Epidemiol. 1999;9(2):158-66. Go to original source... Go to PubMed...
    21. Czech Hydrometeorological Institute [Internet]. 2018 [cited 2018 July 12]. Available from: http://portal.chmi.cz/?l=en#!.
    22. Xu H, Cao J, Gao M, Ho KF, Niu X, Coons TL, et al. Personal exposure to fine particulates and polycyclic aromatic hydrocarbons in an office environment in Xi'an, China. Front Environ Sci. 2013;2(4):33-45.
    23. Liu LB, Hashi Y, Liu M, Wei Y, Lin JM. Determination of particle-associated polycyclic aromatic hydrocarbons in urban air of Beijing by GC/MS. Anal Sci. 2007;23(6):667-71. Go to original source... Go to PubMed...
    24. Wei Y, Han IK, Hu M, Shao M, Zhang JJ, Tang X. Personal exposure to particulate PAHs and anthraquinone and oxidative DNA damages in humans. Chemosphere. 2010;81(10):1280-5. Go to original source... Go to PubMed...
    25. Rogula-Kozłowska W, Klejnowski K, Rogula-Kopiec P, O¶ródka L, Krajny E, Błaszczak B, et al. Spatial and seasonal variability of the mass concentration and chemical composition of PM2.5 in Poland. Air Qual Atmos Health. 2014;7(1):41-58. Go to original source... Go to PubMed...
    26. Sovinová H, Csémy L. The use of tobacco and alcohol in the Czech Republic 2012 [Internet]. National Institute of Public Health; 2013 [cited 2017 March 10]. Available from: http://www.szu.cz/uploads/documents/czzp/zavislosti/TabAlkoAngl.pdf.
    27. Perera FP, Wheelock K, Wang Y, Tang D, Margolis AE, Badia G, et al. Combined effects of prenatal exposure to polycyclic aromatic hydrocarbons and material hardship on child ADHD behavior problems. Environ Res. 2018;160:506-13. Go to original source... Go to PubMed...
    28. Sram RJ, Binkova B, Dostal M, Merkerova-Dostalova M, Libalova H, Milcova A, et al. Health impact of air pollution to children. Int J Hyg Environ Health. 2013;216(5):533-40. Go to original source... Go to PubMed...
    29. Yang WS, Wang X, Deng Q, Fan WY, Wang WY. An evidence-based appraisal of global association between air pollution and risk of stroke. Int J Cardiol. 2014;175(2):307-13. Go to original source... Go to PubMed...
    30. Ren J, Li B, Yu D, Liu J, Ma Z. Approaches to prevent the patients with chronic airway diseases from exacerbation in the haze weather. J Thorac Dis. 2016;8(1):E1-7. Go to PubMed...
    31. Gao J, Woodward A, Vardoulakis S, Kovats S, Wilkinson P, Li L, et al. Haze, public health and mitigation measures in China: a review of the current evidence for further policy response. Sci Total Environ. 2017;578:148-57. Go to original source... Go to PubMed...
    32. ©auer P, Kreuz J, Lisa A. Assessing efforts to mitigate particulate matter air pollution in the Moravian-Silesian Region. Pol J Environ Stud. 2014;23(6):2233-42.
    33. Balasubramanian R, Lee SS. Characteristics of indoor aerosols in residential homes in urban locations: a case study in Singapore. J Air Waste Manag Assoc. 2007;57(8):981-90. Go to original source... Go to PubMed...
    34. Zhang S, Li L, Gao W, Wang Y, Yao X. Interventions to reduce individual exposure of elderly individuals and children to haze: a review. J Thorac Dis. 2016;8(1):E62-8. Go to PubMed...

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