Welcome to DeutEx website
This web page is dedicated to software DeutEx that is used to process and visualize data from hydrogen/deuterium exchange mass spectrometry experiments.
Once fully developed, it will contain complete wiki-based documentation serving as a help/manual, eventually the links to a BitBucket repository and Mantis bug reporting system. You can check the list of the papers published with the use of the program. Software is now being jointly developed in collaboration with Bruker Daltonics and cannot be freely distributed.
DeutEx is a java based standalone program, primarily developed for processing of high-resolution, high mass accuracy MS data acquired using Bruker FT-ICR MS.
However, it can cope with data from other instruments. Currently, it is routinely used for processing of dataset from timsTOF Pro.
It is not reading the original raw data but works with data exported to open-access format. It performs all steps of HDX-MS workflow including peptide mapping,
calculation of deuteration of all peptides within the dataset and basic visualization of the results and their export according to the guidelines.
DeutEx was developed by members of the Laboratory of Structural Biology and Cell Signalling (aka peterslab) at the Institute of Microbiology,
Academy of Sciences of the Czech Republic. Initial xmass script written by Gary H. Kruppa was later adopted and redesigned into the current version by Daniel Kavan,
development and testing were driven by Petr Man and Alan Kadek.