STRONG INADEQUATE, an Experiment for Detection of Small J(C,C) Couplings in Symmetrical Molecules.

0512033 - ÚCHP 2020 RIV GB eng J - Článek v odborném periodiku
Blechta, Vratislav - Sýkora, Jan
STRONG INADEQUATE, an Experiment for Detection of Small J(C,C) Couplings in Symmetrical Molecules.
Magnetic Resonance in Chemistry. Roč. 57, č. 12 (2019), s. 1107-1120. ISSN 0749-1581. E-ISSN 1097-458X
Grant CEP: GA ČR GA15-12719S
Institucionální podpora: RVO:67985858
Klíčová slova: carbon–carbon coupling * equivalent carbons * INADEQUATE
Obor OECD: Physical chemistry
Impakt faktor: 2.035, rok: 2019
Způsob publikování: Omezený přístup

A new version of the two-dimensional INADEQUATE experiment was designed for detection of small couplings between equivalent carbon atoms separated in the molecule by several bonds, where other techniques fail due to rich line splitting and mutual peak cancellation in many molecules. As the proposed method is suitable for detection of couplings in strongly coupled systems in general, we propose the name STRONG INADEQUATE in the paper. Similar to other methods for detection of couplings between equivalent carbons, the STRONG INADEQUATE experiment utilizes one-bond carbon–proton coupling for creation of the effective chemical shift differences. The STRONG INADEQUATE experiment works superbly for nJCC, where n ≥ 3. Then the F1 pattern is reduced to a simple antiphase doublet with nJCC separation, and this pattern is also preserved when a symmetrical HC···C′H′ system is coupled to other protons. Even in the measurement of 2JCC couplings, the STRONG INADEQUATE experiment generates a much simpler pattern than the original pulse sequences for measurement of couplings between equivalent carbons.
Trvalý link: http://hdl.handle.net/11104/0302246