Use of Microwave Heating in the Synthesis of Novel Polysaccharide Derivatives.

0472894 - ÚCHP 2017 RIV CZ eng C - Konferenční příspěvek (zahraniční konf.)
Taubner, T. - Synytsia, A. - Sobek, Jiří - Kortanková, V. - Čopíková, J.
Use of Microwave Heating in the Synthesis of Novel Polysaccharide Derivatives.
Proceedings of the 11th International Conference on Polysaccharides-Glycoscience. Prague: Czech Chemical Society, 2015 - (Řápková, R.; Čopíková, J.), s. 183-186. ISBN 978-80-86238-85-2. ISSN 2336-6796.
[International Conference on Polysaccharides-Glycoscience /11./. Prague (CZ), 07.10.2015-09.10.2015]
Institucionální podpora: RVO:67985858
Klíčová slova: amidated derivatives * microwave * polysaccharides
Kód oboru RIV: CI - Průmyslová chemie a chemické inženýrství

Microwave-assisted modification of polysaccharides is a relatively new method. Microwave heating is used for improving of extraction, hydrolytic and synthetic procedures. Modification of polysaccharides with the microwave irradiation is effective, fast and economic. The aim of this study was to apply the microwave irradiation in synthesis of carboxymethylcellulose (CMC) derivatives. This polysaccharide and its methyl ester reacted with n-butylamine yielding N-butylamide. The reactions were subsequently monitored by FUR and organic elemental analysis of the products. Degree of substitution (DS) and reaction yields were calculated based on nitrogen and carbon contents. The optimal reaction conditions were found to prepare product with the highest DS. Amino-de-alkoxylation of CMC methyl ester was significantly more effective than direct microwave assisted amidation of CMC, and microwave assisted significantly improved amino-de-alkoxylation.
Trvalý link: http://hdl.handle.net/11104/0270103