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Bimetallic nanowires on laser-patterned PEN as promising biomaterials
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SYSNO ASEP 0547750 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Bimetallic nanowires on laser-patterned PEN as promising biomaterials Tvůrce(i) Pryjmaková, J. (CZ)
Kaimlová, M. (CZ)
Vokatá, B. (CZ)
Hubáček, Tomáš (BC-A) RID
Slepička, P. (CZ)
Svorčík, V. (CZ)
Siegel, J. (CZ)Číslo článku 2285 Zdroj.dok. Nanomaterials. - : MDPI
Roč. 11, č. 9 (2021)Poč.str. 15 s. Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova surface modification ; nanostructure ; polymer ; bimetallic nanowires ; biocompatibility ; antibacterial properties Vědní obor RIV JP - Průmyslové procesy a zpracování Obor OECD Materials engineering Způsob publikování Open access Institucionální podpora BC-A - RVO:60077344 UT WOS 000700160800001 EID SCOPUS 85114084317 DOI 10.3390/nano11092285 Anotace As inflammation frequently occurs after the implantation of a medical device, biocompatible, antibacterial materials must be used. Polymer-metal nanocomposites are promising materials. Here we prepared enhanced polyethylene naphthalate (PEN) using surface modification techniques and investigated its suitability for biomedical applications. The PEN was modified by a KrF laser forming periodic ripple patterns with specific surface characteristics. Next, Au/Ag nanowires were deposited onto the patterned PEN using vacuum evaporation. Atomic force microscopy confirmed that the surface morphology of the modified PEN changed accordingly with the incidence angle of the laser beam. Energy-dispersive X-ray spectroscopy showed that the distribution of the selected metals was dependent on the evaporation technique. Our bimetallic nanowires appear to be promising antibacterial agents due to the presence of antibacterial noble metals. The antibacterial effect of the prepared Au/Ag nanowires against E. coli and S. epidermidis was demonstrated using 24 h incubation with a drop plate test. Moreover, a WST-1 cytotoxicity test that was performed to determine the toxicity of the nanowires showed that the materials could be considered non-toxic. Collectively, these results suggest that prepared Au/Ag nanostructures are effective, biocompatible surface coatings for use in medical devices. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2022 Elektronická adresa https://www.mdpi.com/2079-4991/11/9/2285
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