Počet záznamů: 1  

Plasma-Activated Polyvinyl Alcohol Foils for Cell Growth

  1. 1.
    SYSNO ASEP0537924
    Druh ASEPJ - Článek v odborném periodiku
    Zařazení RIVJ - Článek v odborném periodiku
    Poddruh JČlánek ve WOS
    NázevPlasma-Activated Polyvinyl Alcohol Foils for Cell Growth
    Tvůrce(i) Kasálková-Slepičková, N. (CZ)
    Slepička, P. (CZ)
    Ivanovská, B. (CZ)
    Trávníčková, Martina (FGU-C) RID, ORCID
    Malinský, Petr (UJF-V) RID, ORCID
    Macková, Anna (UJF-V) RID, ORCID
    Bačáková, Lucie (FGU-C) RID, ORCID
    Švorčík, V. (CZ)
    Číslo článku1083
    Zdroj.dok.Coatings
    Roč. 10, č. 11 (2020)
    Poč.str.20 s.
    Jazyk dok.eng - angličtina
    Země vyd.CH - Švýcarsko
    Klíč. slovacytocompatibility ; nanoparticle doping ; plasma treatment ; polymer ; PVA ; surface characterization ; tissue engineering
    Vědní obor RIVEI - Biotechnologie a bionika
    Obor OECDBiomaterials (as related to medical implants, devices, sensors)
    Vědní obor RIV – spolupráceÚstav jaderné fyziky - Jaderná, atomová a mol. fyzika, urychlovače
    CEPGA19-02482S GA ČR - Grantová agentura ČR
    Způsob publikováníOpen access
    Institucionální podporaFGU-C - RVO:67985823 ; UJF-V - RVO:61389005
    UT WOS000592729900001
    DOI10.3390/coatings10111083
    AnotaceHydrogels, and not only natural polysaccharide hydrogels, are substances capable of absorbing large amounts of water and physiological fluids. In this study, we set out to optimize the process for preparing polyvinyl alcohol (PVA) hydrogels. Subsequently, we doped PVA foils with cellulose powder, with poly(ethylene glycol) (PEG) or with gold nanoparticles in PEG colloid solutions (Au). The foils were then modified in a plasma discharge to improve their biocompatibility. The properties of PVA foils were studied by various analytical methods. The use of a suitable dopant can significantly affect the surface wettability, the roughness, the morphology and the mechanical properties of the material. Plasma treatment of PVA leads to ultraviolet light-induced crosslinking and decreasing water absorption. At the same time, this treatment significantly improves the cytocompatibility of the polymer, which is manifested by enhanced growth of human adipose-derived stem cells. This positive effect on the cell behavior was most pronounced on PVA foils doped with PEG or with Au. This modification of PVA therefore seems to be most suitable for the use of this polymer as a cell carrier for tissue engineering, wound healing and other regenerative applications.
    PracovištěFyziologický ústav
    KontaktLucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
    Rok sběru2021
    Elektronická adresahttps://www.mdpi.com/2079-6412/10/11/1083
Počet záznamů: 1