Počet záznamů: 1

Designing Porphyrinic Covalent Organic Frameworks for the Photodynamic Inactivation of Bacteria

SYSNO ASEP	0488571
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Designing Porphyrinic Covalent Organic Frameworks for the Photodynamic Inactivation of Bacteria
Tvůrce(i)	Hynek, Jan (UACH-T)_{SAI, RID, ORCID} Zelenka, J. (CZ) Rathouský, Jiří (UFCH-W)_{RID, ORCID} Kubát, Pavel (UFCH-W)_{RID, ORCID, SAI} Ruml, T. (CZ) Demel, Jan (UACH-T)_{SAI, RID, ORCID} Lang, Kamil (UACH-T)_{SAI, RID, ORCID}
Zdroj.dok.	ACS Applied Materials and Interfaces. - : American Chemical Society - ISSN 1944-8244 Roč. 10, č. 10 (2018), s. 8527-8535
Poč.str.	9 s.
Jazyk dok.	eng - angličtina
Země vyd.	US - Spojené státy americké
Klíč. slova	antibacterial coating ; biofilm ; covalent organic framework ; photodynamic ; porphyrin ; singlet oxygen
Vědní obor RIV	CA - Anorganická chemie
Obor OECD	Inorganic and nuclear chemistry
Vědní obor RIV – spolupráce	Ústav fyzikální chemie J.Heyrovského - Fyzikální chemie a teoretická chemie
CEP	GA16-15020S GA ČR - Grantová agentura ČR
Institucionální podpora	UACH-T - RVO:61388980 ; UFCH-W - RVO:61388955
UT WOS	000427910800016
EID SCOPUS	85043779819
DOI	10.1021/acsami.7b19835
Anotace	Microbial colonization of biomedical devices is a recognized complication contributing to healthcare-associated infections. One of the possible approaches to prevent surfaces from the biofilm formation is antimicrobial photodynamic inactivation based on the cytotoxic effect of singlet oxygen, O 2 ( 1 Δ g ), a short-lived, highly oxidative species, produced by energy transfer between excited photosensitizers and molecular oxygen. We synthesized porphyrin-based covalent organic frameworks (COFs) by Schiff-base chemistry. These novel COFs have a three-dimensional, diamond-like structure. The detailed analysis of their photophysical and photochemical properties shows that the COFs effectively produce O 2 ( 1 Δ g ) under visible light irradiation, and especially three-dimensional structures have strong antibacterial effects toward Pseudomonas aeruginosa and Enterococcus faecalis biofilms. The COFs exhibit high photostability and broad spectral efficiency. Hence, the porphyrinic COFs are suitable candidates for the design of antibacterial coating for indoor applications.
Pracoviště	Ústav anorganické chemie
Kontakt	Jana Kroneislová, krone@iic.cas.cz, Tel.: 311 236 931
Rok sběru	2019

Počet záznamů: 1