Počet záznamů: 1  

RIN4 recruits the exocyst subunit EXO70B1 to the plasma membrane

  1. 1.
    SYSNO ASEP0478867
    Druh ASEPJ - Článek v odborném periodiku
    Zařazení RIVJ - Článek v odborném periodiku
    Poddruh JČlánek ve WOS
    NázevRIN4 recruits the exocyst subunit EXO70B1 to the plasma membrane
    Tvůrce(i) Sabol, P. (CZ)
    Kulich, I. (CZ)
    Žárský, Viktor (UEB-Q) RID, ORCID
    Celkový počet autorů3
    Zdroj.dok.Journal of Experimental Botany. - : Oxford University Press - ISSN 0022-0957
    Roč. 68, č. 12 (2017), s. 3253-3265
    Poč.str.13 s.
    Jazyk dok.eng - angličtina
    Země vyd.GB - Velká Británie
    Klíč. slovaoligomeric golgi-complex ; powdery mildew fungus ; pseudomonas-syringae ; cell polarity ; arabidopsis ; protein ; plants ; resistance ; expression ; transport ; Autophagy ; exo70b1 ; exo70b2 ; exocyst ; plant immunity ; rin4 ; secretion
    Vědní obor RIVEB - Genetika a molekulární biologie
    Obor OECDPlant sciences, botany
    CEPGA15-14886S GA ČR - Grantová agentura ČR
    Institucionální podporaUEB-Q - RVO:61389030
    UT WOS000407488500019
    DOI10.1093/jxb/erx007
    AnotaceThe exocyst is a conserved vesicle-tethering complex with principal roles in cell polarity and morphogenesis. Several studies point to its involvement in polarized secretion during microbial pathogen defense. In this context, we have found an interaction between the Arabidopsis EXO70B1 exocyst subunit, a protein which was previously associated with both the defense response and autophagy, and RPM1 INTERACTING PROTEIN 4 ( RIN4), the best studied member of the NOI protein family and a known regulator of plant defense pathways. Interestingly, fragments of RIN4 mimicking the cleavage caused by the Pseudomonas syringae effector protease, AvrRpt2, fail to interact strongly with EXO70B1. We observed that transiently expressed RIN4, but not the plasma membrane ( PM) protein aquaporin PIP2, recruits EXO70B1 to the PM. Unlike EXO70B1, RIN4 does not recruit the core exocyst subunit SEC6 to the PM under these conditions. Furthermore, the AvrRpt2 effector protease delivered by P. syringae is able to release both RIN4 and EXO70B1 to the cytoplasm. We present a model for how RIN4 might regulate the localization and putative function of EXO70B1 and speculate on the role the AvrRpt2 protease might have in the regulation of this defense response.
    PracovištěÚstav experimentální botaniky
    KontaktDavid Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469
    Rok sběru2018
Počet záznamů: 1  

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