Počet záznamů: 1
Isolation of live Borrelia burgdorferi sensu lato spirochaetes from patients with undefined disorders and symptoms not typical for Lyme borreliosis
- 1.
SYSNO ASEP 0463390 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Isolation of live Borrelia burgdorferi sensu lato spirochaetes from patients with undefined disorders and symptoms not typical for Lyme borreliosis Tvůrce(i) Rudenko, Natalia (BC-A) RID, ORCID
Golovchenko, Maryna (BC-A) RID, ORCID
Vancová, Marie (BC-A) RID, ORCID
Clark, K. (US)
Grubhoffer, Libor (BC-A) RID, ORCID
Oliver, J. H., Jr. (US)Zdroj.dok. Clinical Microbiology and Infection - ISSN 1198-743X
Roč. 22, č. 3 (2016), 267.e9-267.e15Poč.str. 7 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. CA - Kanada Klíč. slova antibiotic treatment ; live Borrelia burgdorferi ; live Borrelia bissettii ; Lyme borreliosis ; recovery of live spirochaetes Vědní obor RIV FN - Epidemiologie, infek. nemoci a klin. imunologie Institucionální podpora BC-A - RVO:60077344 UT WOS 000372083500015 EID SCOPUS 84959495382 DOI 10.1016/j.cmi.2015.11.009 Anotace Lyme borreliosis is a multisystem disorder with a diverse spectrum of clinical manifestations, caused by spirochaetes of the Borrelia burgdorferi sensu lato complex. It is an infectious disease that can be successfully cured by antibiotic therapy in the early stages; however, the possibility of the appearance of persistent signs and symptoms of disease following antibiotic treatment is recognized. It is known that Lyme borreliosis mimics multiple diseases that were never proven to have a spirochaete aetiology. Using complete modified Kelly- Pettenkofer medium we succeeded in cultivating live B. burgdorferi sensu lato spirochaetes from samples taken from people who suffered from undefined disorders, had symptoms not typical for Lyme borreliosis, but who had undergone antibiotic treatment due to a suspicion of having Lyme disease even though they were seronegative. We report the first recovery of live B. burgdorferi sensu stricto from residents of southeastern USA and the first successful cultivation of live Borrelia bissettii- like strain from residents of North America. Our results support the fact that B. bissettii is responsible for human Lyme borreliosis worldwide along with B. burgdorferi s. s. The involvement of new spirochaete species in Lyme borreliosis changes the understanding and recognition of clinical manifestations of this disease. Clinical Microbiology and Infection (C) 2016 European Society of Clinical Microbiology and Infectious Diseases. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2017
Počet záznamů: 1