Počet záznamů: 1
Fungal microsomes in a biotransformation perspective: protein nature of membrane-associated reactions
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SYSNO ASEP 0422882 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Fungal microsomes in a biotransformation perspective: protein nature of membrane-associated reactions Tvůrce(i) Svobodová, Kateřina (MBU-M) RID
Mikesková, Hana (MBU-M) RID
Petráčková, Denisa (MBU-M) RID, ORCIDZdroj.dok. Applied Microbiology and Biotechnology. - : Springer - ISSN 0175-7598
Roč. 97, č. 24 (2013), s. 10263-10273Poč.str. 11 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova Fungal microsomes ; Cytochrome P450 ; Biodegradation Vědní obor RIV EE - Mikrobiologie, virologie CEP TE01020218 GA TA ČR - Technologická agentura ČR Institucionální podpora MBU-M - RVO:61388971 UT WOS 000327495000003 DOI 10.1007/s00253-013-5347-2 Anotace Microsomal fraction of fungal cells grabs the attention of many researchers for it contains enzymes that play a role in biotechnologically relevant processes. Microsomal enzymes, namely, CYP450s, were shown to metabolize a wide range of xenobiotic compounds, including PAHs, PCBs, dioxins, and endocrine disruptors, and take part in other fungal biotransformation reactions. However, little is known about the nature and regulation of these membrane-associated reactions. Advanced proteomic and post-genomic techniques make it possible to identify larger numbers of microsomal proteins and thus add to a deeper study of fungal intracellular processes. In this work, proteins that were identified through a shotgun proteomic approach in fungal microsomes under various culture conditions are reviewed. However, further research is still needed to fully understand the role of microsomes in fungal biodegradation and biotransformation reactions Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2014
Počet záznamů: 1