Počet záznamů: 1
Vitamin D in colorectal, breast, prostate and lung cancer: A pilot study
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SYSNO ASEP 0382434 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Vitamin D in colorectal, breast, prostate and lung cancer: A pilot study Tvůrce(i) Padziora, P. (CZ)
Svobodová, Š. (CZ)
Fuchsová, R. (CZ)
Kučera, R. (CZ)
Pražáková, M. (CZ)
Vrzalová, J. (CZ)
Ňaršanská, A. (CZ)
Straková, M. (CZ)
Třešková, I. (CZ)
Pecen, Ladislav (UIVT-O) RID, SAI, ORCID
Třeška, V. (CZ)
Holubec jr., L. (CZ)
Pešek, M. (CZ)
Finek, J. (CZ)
Topolčan, O. (CZ)Zdroj.dok. Anticancer Research. - : International Institute of Anticancer Research - ISSN 0250-7005
Roč. 31, č. 10 (2011), s. 3619-3621Poč.str. 3 s. Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. GR - Řecko Klíč. slova vitamin D ; colorectal cancer ; breast cancer ; prostate cancer ; lung cancer Vědní obor RIV FD - Onkologie a hematologie CEZ AV0Z10300504 - UIVT-O (2005-2011) UT WOS 000295667700072 EID SCOPUS 80054761307 Anotace Background: Many studies have demonstrated the relationship between vitamin D and cancer of many different sites, including of the breast, colorectum, prostate and lung. Most epidemiological studies have assessed the effects of dietary intake only, although endogenous production after sun exposure is the main source of vitamin D. The aim of our pilot study was to study serum levels of vitamin D in general population and in patients with different type of cancer. Patients and Methods: The control group consisted of 214 healthy individuals. Pathological groups of patients included 170 patients with different cancer types (28 patients with prostate cancer, 43 patients with breast cancer, 49 patients with colorectal cancer and 50 patients with lung cancer). All of the patients were enrolled in the early clinical stage of cancer up to clinical stage III. Advanced stages were not included into the study. Vitamin D serum levels were measured using ECLIA Roche method. Results: All the results for serum vitamin D from pathological groups were significantly lower compared to the levels of the control group. All the cancer types had a high incidence rate of very low serum levels of vitamin D. Lung cancer had the highest incidence rate of very low vitamin D serum levels. Conclusion: We found a high incidence of hypovitaminosis D in cancer patients compared to a healthy control group among a Czech population. This incidence rate is higher in comparison to data found in literature from the other parts of the world. Based on the data from this study, a large epidemiological study monitoring vitamin D serum levels in the healthy population and in cancer patients in the Czech Republic has been already proposed. Pracoviště Ústav informatiky Kontakt Tereza Šírová, sirova@cs.cas.cz, Tel.: 266 053 800 Rok sběru 2013
Počet záznamů: 1