Počet záznamů: 1
Polyglutamate copolymers as a tissue-engineering platform: polymer scaffold modification through aminolysis of poly(.gamma.-benzyl-L-glutamate-co-2,2,2-.gamma.-trichlorethyl-L-glutamate)
- 1.
SYSNO ASEP 0369730 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Polyglutamate copolymers as a tissue-engineering platform: polymer scaffold modification through aminolysis of poly(.gamma.-benzyl-L-glutamate-co-2,2,2-.gamma.-trichlorethyl-L-glutamate) Tvůrce(i) Svobodová, Jana (UMCH-V) RID, ORCID
Rypáček, František (UMCH-V) RIDZdroj.dok. European Polymer Journal. - : Elsevier - ISSN 0014-3057
Roč. 48, č. 1 (2012), s. 183-190Poč.str. 8 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova poly(.gamma.-benzyl-L-glutamate) ; 2,2,2-.gamma.-trichlorethyl-L-glutamate ; fibres Vědní obor RIV CD - Makromolekulární chemie CEP KJB400500904 GA AV ČR - Akademie věd GAP108/11/1857 GA ČR - Grantová agentura ČR 1M0538 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy CEZ AV0Z40500505 - UMCH-V (2005-2011) UT WOS 000300078700019 DOI 10.1016/j.eurpolymj.2011.10.019 Anotace Homopolymers of γ-benzyl-L-glutamate (BLG) and its copolymers with more reactive 2,2,2-γ-trichlorethyl-L-glutamate (TCEG) were synthesized by ROP of respective N-carboxyanhydrides (NCA). The feasibility of functional modification of polyglutamate films and fibres through aminolysis of glutamate side chains with 2-aminoethanol or with a 2-aminoethanol/1,6-diaminohexane mixture was studied. The progress and extent of polymer side chain modification were analyzed by following methods: (a) the conversion of aminolysis of BLG units alone was determined from the amount of released benzyl alcohol extracted into hexane and followed by HPLC analysis, (b) the conversion of aminolysis of TCEG units was calculated from elemental analysis, (c) the depth and extend of films surface modification was evaluated ATR IR measurements and (d) the amount of free amino groups, created by aminolysis with 1,6-diaminohexane, was quantified by reaction with 2,4,6-trinitrobenzenesulfonic acid. Pracoviště Ústav makromolekulární chemie Kontakt Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Rok sběru 2012
Počet záznamů: 1