Počet záznamů: 1
Tetrapyrrole Synthesis of Photosynthetic Chromerids Is Likely Homologous to the Unusual Pathway of Apicomplexan Parasites
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SYSNO ASEP 0367760 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Tetrapyrrole Synthesis of Photosynthetic Chromerids Is Likely Homologous to the Unusual Pathway of Apicomplexan Parasites Tvůrce(i) Kořený, Luděk (BC-A) RID
Sobotka, Roman (MBU-M) RID, ORCID
Janouškovec, J. (CZ)
Keeling, P. J. (CA)
Oborník, Miroslav (BC-A) RID, ORCIDZdroj.dok. Plant Cell. - : Oxford University Press - ISSN 1040-4651
Roč. 23, č. 9 (2011), s. 3454-3462Poč.str. 10 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova YEAST SACCHAROMYCES-CEREVISIAE ; HEME-BIOSYNTHESIS PATHWAY ; PLASMODIUM-FALCIPARUM ; MALARIA PARASITE ; 5-AMINOLEVULINATE SYNTHASE ; SECONDARY PLASTIDS ; TOXOPLASMA-GONDII ; PROTEIN-TRANSPORT ; EUGLENA-GRACILIS ; METABOLIC MAPS Vědní obor RIV EB - Genetika a molekulární biologie CEP GA206/08/1423 GA ČR - Grantová agentura ČR IAA601410907 GA AV ČR - Akademie věd CEZ AV0Z60220518 - PAU-O, BC-A (2005-2011) AV0Z50200510 - MBU-M (2005-2011) UT WOS 000296739100030 DOI 10.1105/tpc.111.089102 Anotace Most photosynthetic eukaryotes synthesize both heme and chlorophyll via a common tetrapyrrole biosynthetic pathway starting from glutamate. This pathway was derived mainly from cyanobacterial predecessor of the plastid and differs from the heme synthesis of the plastid-lacking eukaryotes. Here, we show that the coral-associated alveolate Chromera velia, the closest known photosynthetic relative to Apicomplexa, possesses a tetrapyrrole pathway that is homologous to the unusual pathway of apicomplexan parasites. We also demonstrate that, unlike other eukaryotic phototrophs, Chromera synthesizes chlorophyll from glycine and succinyl-CoA rather than glutamate. Our data shed light on the evolution of the heme biosynthesis in parasitic Apicomplexa and photosynthesis-related biochemical processes in their ancestors. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2012
Počet záznamů: 1