Počet záznamů: 1
Fibrinogen-related proteins in ixodid ticks
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SYSNO ASEP 0364780 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Fibrinogen-related proteins in ixodid ticks Tvůrce(i) Štěrba, J. (CZ)
Dupejová, J. (CZ)
Fišer, M. (CZ)
Vancová, Marie (BC-A) RID, ORCID
Grubhoffer, Libor (BC-A) RID, ORCIDZdroj.dok. Parasites & Vectors. - : BioMed Central - ISSN 1756-3305
Roč. 4, - (2011), e127Poč.str. 10 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova AMERICAN DOG TICK ; INNATE IMMUNITY ; DORIN-M ; RHIPICEPHALUS-APPENDICULATUS ; MOLECULAR CHARACTERIZATION ; DERMACENTOR-VARIABILIS ; ORNITHODOROS-MOUBATA ; LECTINS ; HEMOLYMPH ; BINDING Vědní obor RIV EE - Mikrobiologie, virologie CEP LC06009 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy KJB600960906 GA AV ČR - Akademie věd GA206/09/1782 GA ČR - Grantová agentura ČR CEZ AV0Z60220518 - PAU-O, BC-A (2005-2011) UT WOS 000292963400001 DOI 10.1186/1756-3305-4-127 Anotace Fibrinogen-related proteins with lectin activity are believed to be part of the tick innate immune system. Some of them were detected in high abundance in the haemolymph of ixodid ticks Dermacentor marginatus, Rhipicephalus appendiculatus, R. pulchellus, and R. sanguineus. These proteins were recognised by sera directed against the tick lectin Dorin M and the haemagglutination activity of the ticks R. appendiculatus and D. marginatus. The fibrinogen-related proteins were shown to be glycosylated and they were localised in salivary glands, midguts, and haemocytes of D. marginatus. The detected proteins have potential as targets for anti-tick vaccines and as antimicrobial proteins in pharmacology. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2012
Počet záznamů: 1