Počet záznamů: 1

DNA Replication-Current Advances

SYSNO ASEP	0364291
Druh ASEP	M - Kapitola v monografii
Zařazení RIV	C - Kapitola v knize
Název	Telomore maintenance on organisms without telomerase
Tvůrce(i)	Mason, J. M. (US) Reddy, H. M. (US) Čapková Frydrychová, Radmila (BC-A)_{RID, ORCID}
Celkový počet autorů	3
Zdroj.dok.	DNA Replication-Current Advances. - Rijeka : InTech, 2011 / Seligmann Herve - ISBN 978-953-307-593-8
Rozsah stran	s. 323-346
Poč.str.	24 s.
Poč.výt.	350
Poč.str.knihy	694
Jazyk dok.	eng - angličtina
Země vyd.	HR - Chorvatsko
Klíč. slova	telomere
Vědní obor RIV	EB - Genetika a molekulární biologie
CEZ	AV0Z50070508 - ENTU-I, BC-A (2005-2011)
Anotace	Most eukaryotes elongate chromosome ends with telomerase that repeatedly adds copies of the short telomeric DNA sequence to the chromosome end. While there is strict conservation of telomeric sequence repeat in most species, the repeat unit has changed over evolutionary time. Lack of the predominant telomeric sequence in a species does not, however, signify that telomerase-generated terminal sequences are missing. Conversely, the presence of a canonical telomeric sequence does not necessarily indicate telomerase as a telomere maintenance mechanism. Although telomerase may have been the mechanism of telomere maintenance of the last common eukaryotic ancestor, it is not the only mechanism used to maintain chromosome length. Telomerase has been lost a few times in the evolution of plants and animals. During insect evolution, for example, telomerase has been lost at least six times. Here, we discuss telomere maintenance mechanisms that replaced telomerase in telomere length maintenance.
Pracoviště	Biologické centrum (od r. 2006)
Kontakt	Dana Hypšová, eje@eje.cz, Tel.: 387 775 214
Rok sběru	2012

Počet záznamů: 1