Počet záznamů: 1

Biomarkers of exposure and effect – interpretation for human risk

SYSNO ASEP	0363581
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Biomarkers of exposure and effect – interpretation for human risk
Tvůrce(i)	Šrám, Radim (UEM-P)_RID Binková, B. (CZ) Beskid, Olena (UEM-P) Milcová, Alena (UEM-P) Rössner, P. (CZ) Rössner ml., Pavel (UEM-P)_{RID, ORCID} Rössnerová, Andrea (UEM-P)_RID Solanský, I. (CZ) Topinka, Jan (UEM-P)_{RID, ORCID}
Zdroj.dok.	Air Quality, Atmosphere and Health (AQAH) - ISSN 1873-9318 Roč. 4, č. 3 (2011), s. 161-167
Poč.str.	9 s.
Jazyk dok.	eng - angličtina
Země vyd.	NL - Nizozemsko
Klíč. slova	personal monitoring ; benzo[a]pyrene ; carcinogenic polycyclic aromatic hydrocarbons
Vědní obor RIV	DN - Vliv životního prostředí na zdraví
CEP	SL/5/160/05 GA MŽP - Ministerstvo životního prostředí
	SP/1B3/8/08 GA MŽP - Ministerstvo životního prostředí
CEZ	AV0Z50390512 - UEM-P (2005-2011)
UT WOS	000309479900002
EID SCOPUS	80051694260
DOI	10.1007/s11869-011-0133-8
Anotace	The effect of exposure to carcinogenic PAHs adsorbed onto respirable air particles on DNA adducts and chromosomal aberrations was repeatedly studied in groups of policemen and bus drivers from Prague, Czech Republic. Personal exposure was evaluated using personal samplers during working shifts. DNA adducts were analyzed in lymphocytes by the 32P-postlabeling assay and chromosomal aberrations by conventional cytogenetic analysis and by fluorescent in situ hybridization (FISH). The studies suggest that the environmental exposure of nonsmokers to concentrations higher than 1 ng B[a]P/m3 represents a risk to DNA damage, as indicated by an increase in DNA adducts and in the genomic frequency of translocations determined by FISH.
Pracoviště	Ústav experimentální medicíny
Kontakt	Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
Rok sběru	2012

Počet záznamů: 1