Počet záznamů: 1
Surface-initiated polymerization of 2-hydroxyethyl methacrylate from heterotelechelic oligoperoxide-coated .gamma.-Fe2O3 nanoparticles and their engulfment by mammalian cells
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SYSNO ASEP 0359776 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Surface-initiated polymerization of 2-hydroxyethyl methacrylate from heterotelechelic oligoperoxide-coated .gamma.-Fe2O3 nanoparticles and their engulfment by mammalian cells Tvůrce(i) Horák, Daniel (UMCH-V) RID, ORCID
Shagotova, Tetiana (UMCH-V)
Mitina, N. (UA)
Trchová, Miroslava (UMCH-V) RID, ORCID
Boiko, N. (UA)
Babič, Michal (UMCH-V) RID, ORCID
Stoika, R. (UA)
Kovářová, Jana (UMCH-V) RID
Hevus, O. (UA)
Beneš, Milan J. (UMCH-V) RID
Klyuchivska, O. (UA)
Holler, Petr (UMCH-V)
Zaichenko, A. (UA)Zdroj.dok. Chemistry of Materials. - : American Chemical Society - ISSN 0897-4756
Roč. 23, č. 10 (2011), s. 2637-2649Poč.str. 13 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova 2-hydroxyethyl methacrylate ; oligoperoxide ; surface-initiated polymerization Vědní obor RIV CD - Makromolekulární chemie CEP GA203/09/1242 GA ČR - Grantová agentura ČR GAP503/10/0664 GA ČR - Grantová agentura ČR KAN401220801 GA AV ČR - Akademie věd CEZ AV0Z40500505 - UMCH-V (2005-2011) UT WOS 000290594700020 DOI 10.1021/cm2004215 Anotace Poly(N-vinylpyrrolidone) (CPA-PVP-IBMB) containing carboxyl from 4-cyanopentanoic acid (CPA) and peroxide from 1-isopropyl-3(4)-[1-(tert-butyl peroxy)-1-methylethyl]benzene (IBMB) chain transfer agent was synthesized as a surface-active macroinitiator for tailored functionalization of γ-Fe2O3. CPA-PVP-IBMB initiated polymerization of 2-hydroxyethyl methacrylate (HEMA) yielding CPA-PVP-block-poly(2-hydroxyethyl methacrylate) (CPA-PVP-block-PHEMA). γ-Fe2O3 obtained by precipitation was modified by CPA-PVP-IBMB and CPA-PVP-block-PHEMA by “grafting-to” using carboxyl groups. “Grafting-from” consisted in polymerization of HEMA initiated from surface of CPA-PVP-IBMB-coated γ-Fe2O3 yielding CPA-PVP-IBMB-coated γ-Fe2O3/PHEMA nanoparticles. Tests with mice leukemia L1210 cells confirmed nontoxicity of CPA-PVP-IBMB-coated γ-Fe2O3/PHEMA. CPA-PVP-IBMB-coated γ-Fe2O3/PHEMA nanoparticles were engulfed by murine macrophages J774.2 and magnetically separated from other cells. Pracoviště Ústav makromolekulární chemie Kontakt Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Rok sběru 2012
Počet záznamů: 1