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Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission
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SYSNO ASEP 0359223 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission Tvůrce(i) Schwarz, Alexandra (BC-A)
Juarez, J. A. (PE)
Richards, J. (PE)
Rath, B. (PE)
Machaca, V. Q. (PE)
Castro, Y. E. (PE)
Málaga, E. S. (PE)
Levy, K. (US)
Gilman, R. H. (US)
Bern, C. (US)
Verastegui, M. (PE)
Levy, M. Z. (US)Zdroj.dok. International Journal for Parasitology. - : Elsevier - ISSN 0020-7519
Roč. 41, č. 6 (2011), s. 591-594Poč.str. 4 s. Jazyk dok. eng - angličtina Země vyd. AU - Austrálie Klíč. slova Triatoma infestans ; Impregnated net ; Sentinel guinea pig ; Saliva ; Antibody response Vědní obor RIV EC - Imunologie CEP GPP302/11/P798 GA ČR - Grantová agentura ČR CEZ AV0Z60220518 - PAU-O, BC-A (2005-2011) UT WOS 000291420800001 DOI 10.1016/j.ijpara.2011.02.001 Anotace Insecticide-impregnated nets can kill triatomine bugs, but it remains unclear whether they can protect against Chagas disease transmission. In a field trial in Quequeña, Peru, sentinel guinea pigs placed in intervention enclosures covered by deltamethrin-treated nets showed significantly lower antibody responses to saliva of Triatoma infestans compared with animals placed in pre-existing control enclosures. Our results strongly suggest that insecticide-treated nets prevent triatomine bites and can thereby protect against infection with Trypanosoma cruzi. Anti-salivary immunoassays are powerful new tools to evaluate intervention strategies against Chagas disease. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2012
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